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Safety and efficacy of IL-23 inhibitors in patients with moderate to severe ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials.

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Title: Safety and efficacy of IL-23 inhibitors in patients with moderate to severe ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials.
Authors: Amin HM; Department of Internal Medicine, South Tees Hospital, Middlesbrough, UK., Hasan S; Department of Gastroenterology, University Hospitals of Leicester, Leicester, UK., Abukhater R; Department of Medicine, RAKMHSU, Ras Al Khaimah, United Arab Emirates., Lilley R; South Tyneside and Sunderland Foundation Trust, Sunderland, UK., Atique A; Department of Gastroenterology, South Warwickshire University NHS Foundation Trust, West Midlands, UK., Shoaib MS; Department of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan., Albustanji Q; Department of Internal Medicine, Specialty Hospital, Amman, Jordan., Sadique H; Department of Medicine, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK., Khalid SM; Department of Gastroenterology, The Shrewsbury and Telford Hospital NHS Trust, West Midlands, UK., Hasan A; Department of Medicine, Imperial College London, London, UK. ali.hasan21@imperial.ac.uk., Majeed S; Department of Internal Medicine, University Hospitals of Leicester, Leicester, UK., Shahzad MA; Department of Gastroenterology, Northampton General Hospital NHS Trust, Northampton, UK., Shahzad M; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan., Ahmed M; Department of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan., Ahmed R; National Heart & Lung Institute, Imperial College London, London, UK., Gardezi SA; Department of Gastroenterology, John's Hopkins HealthCare Aramco, Dhahran, Eastern Province, Saudi Arabia.
Source: International journal of colorectal disease [Int J Colorectal Dis] 2025 Dec 30; Vol. 41 (1), pp. 1. Date of Electronic Publication: 2025 Dec 30.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 8607899 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1262 (Electronic) Linking ISSN: 01791958 NLM ISO Abbreviation: Int J Colorectal Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety and efficacy of IL-23 inhibitors in patients with moderate to severe ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials.
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  Data: <searchLink fieldCode="AU" term="%22Amin+HM%22">Amin HM</searchLink>; Department of Internal Medicine, South Tees Hospital, Middlesbrough, UK.<br /><searchLink fieldCode="AU" term="%22Hasan+S%22">Hasan S</searchLink>; Department of Gastroenterology, University Hospitals of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Abukhater+R%22">Abukhater R</searchLink>; Department of Medicine, RAKMHSU, Ras Al Khaimah, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Lilley+R%22">Lilley R</searchLink>; South Tyneside and Sunderland Foundation Trust, Sunderland, UK.<br /><searchLink fieldCode="AU" term="%22Atique+A%22">Atique A</searchLink>; Department of Gastroenterology, South Warwickshire University NHS Foundation Trust, West Midlands, UK.<br /><searchLink fieldCode="AU" term="%22Shoaib+MS%22">Shoaib MS</searchLink>; Department of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.<br /><searchLink fieldCode="AU" term="%22Albustanji+Q%22">Albustanji Q</searchLink>; Department of Internal Medicine, Specialty Hospital, Amman, Jordan.<br /><searchLink fieldCode="AU" term="%22Sadique+H%22">Sadique H</searchLink>; Department of Medicine, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK.<br /><searchLink fieldCode="AU" term="%22Khalid+SM%22">Khalid SM</searchLink>; Department of Gastroenterology, The Shrewsbury and Telford Hospital NHS Trust, West Midlands, UK.<br /><searchLink fieldCode="AU" term="%22Hasan+A%22">Hasan A</searchLink>; Department of Medicine, Imperial College London, London, UK. ali.hasan21@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Majeed+S%22">Majeed S</searchLink>; Department of Internal Medicine, University Hospitals of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Shahzad+MA%22">Shahzad MA</searchLink>; Department of Gastroenterology, Northampton General Hospital NHS Trust, Northampton, UK.<br /><searchLink fieldCode="AU" term="%22Shahzad+M%22">Shahzad M</searchLink>; Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.<br /><searchLink fieldCode="AU" term="%22Ahmed+M%22">Ahmed M</searchLink>; Department of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.<br /><searchLink fieldCode="AU" term="%22Ahmed+R%22">Ahmed R</searchLink>; National Heart & Lung Institute, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gardezi+SA%22">Gardezi SA</searchLink>; Department of Gastroenterology, John's Hopkins HealthCare Aramco, Dhahran, Eastern Province, Saudi Arabia.
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  Data: <searchLink fieldCode="JN" term="%228607899%22">International journal of colorectal disease</searchLink> [Int J Colorectal Dis] 2025 Dec 30; Vol. 41 (1), pp. 1. <i>Date of Electronic Publication: </i>2025 Dec 30.
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              Text: 2025 Dec 30
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