Naphthalimide-nitrosourea derivatives as dual-function antitumor agents for exploration of their action mechanisms and chemical degradation process.

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Bibliographic Details
Title: Naphthalimide-nitrosourea derivatives as dual-function antitumor agents for exploration of their action mechanisms and chemical degradation process.
Authors: Han ZY; Qingdao Key Laboratory of Biomacromolecular Drug Discovery and Development, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China., Jia ZH; Qingdao Key Laboratory of Biomacromolecular Drug Discovery and Development, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China., Meng FX; Qingdao Key Laboratory of Biomacromolecular Drug Discovery and Development, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China., Yu RL; Key laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China., Wang Q; Shandong Xinhua Pharmaceutical Co., Ltd., Zibo 255075, People's Republic of China., Xia YM; Qingdao Key Laboratory of Biomacromolecular Drug Discovery and Development, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China. Electronic address: xiayamu@126.com., Gao WW; Qingdao Key Laboratory of Biomacromolecular Drug Discovery and Development, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, People's Republic of China. Electronic address: gww501@qust.edu.cn.
Source: Bioorganic chemistry [Bioorg Chem] 2026 Feb; Vol. 169, pp. 109435. Date of Electronic Publication: 2025 Dec 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1090-2120
DOI:10.1016/j.bioorg.2025.109435