Gluebodies Offer a Route To Improve Crystal Reliability and Diversity through Transferable Nanobody Mutations That Introduce Constitutive Close Contacts.
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| Title: | Gluebodies Offer a Route To Improve Crystal Reliability and Diversity through Transferable Nanobody Mutations That Introduce Constitutive Close Contacts. |
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| Authors: | Ye M; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Makola M; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Richards MW; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K., Newman JA; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Fairhead M; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Burgess SG; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K., Wu Z; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K., Maclean E; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K.; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, U.K., Wright ND; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Koekemoer L; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Thompson A; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Bezerra GA; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Yi G; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, U.K.; Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, U.K., Li H; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Rangel VL; Laboratory of Protein Crystallography, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo 05508-000, Brazil., Mamalis D; Department of Chemistry, University of Oxford, Oxford OX1 3TA, U.K.; The Rosalind Franklin Institute, Oxfordshire, Oxford OX11 0QS, U.K., Aitkenhead H; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K., Davis BG; Department of Chemistry, University of Oxford, Oxford OX1 3TA, U.K.; The Rosalind Franklin Institute, Oxfordshire, Oxford OX11 0QS, U.K.; Department of Pharmacology, University of Oxford, Oxford OX1 3QT, U.K., Gilbert RJC; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, U.K.; Calleva Research Centre for Evolution and Human Sciences, Magdalen College, University of Oxford, Oxford OX1 4 AU, U.K., Duerr KL; Kavli Institute for Nanoscience Discovery, Department of Chemistry, University of Oxford, Oxford OX1 3QU, U.K., Bayliss R; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, U.K., Gileadi O; SGC Karolinska Center for Molecular Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden., von Delft F; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, U.K.; Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, U.K.; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot OX11 0FA, U.K.; Department of Biochemistry, University of Johannesburg, Auckland Park 2006, South Africa. |
| Source: | ACS central science [ACS Cent Sci] 2025 Oct 27; Vol. 11 (12), pp. 2385-2399. Date of Electronic Publication: 2025 Oct 27 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: ACS Publications Country of Publication: United States NLM ID: 101660035 Publication Model: eCollection Cited Medium: Print ISSN: 2374-7943 (Print) Linking ISSN: 23747943 NLM ISO Abbreviation: ACS Cent Sci Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41473800 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41473800 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acscentsci.5c00937 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2385 Titles: – TitleFull: Gluebodies Offer a Route To Improve Crystal Reliability and Diversity through Transferable Nanobody Mutations That Introduce Constitutive Close Contacts. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ye M – PersonEntity: Name: NameFull: Makola M – PersonEntity: Name: NameFull: Richards MW – PersonEntity: Name: NameFull: Newman JA – PersonEntity: Name: NameFull: Fairhead M – PersonEntity: Name: NameFull: Burgess SG – PersonEntity: Name: NameFull: Wu Z – PersonEntity: Name: NameFull: Maclean E – PersonEntity: Name: NameFull: Wright ND – PersonEntity: Name: NameFull: Koekemoer L – PersonEntity: Name: NameFull: Thompson A – PersonEntity: Name: NameFull: Bezerra GA – PersonEntity: Name: NameFull: Yi G – PersonEntity: Name: NameFull: Li H – PersonEntity: Name: NameFull: Rangel VL – PersonEntity: Name: NameFull: Mamalis D – PersonEntity: Name: NameFull: Aitkenhead H – PersonEntity: Name: NameFull: Davis BG – PersonEntity: Name: NameFull: Gilbert RJC – PersonEntity: Name: NameFull: Duerr KL – PersonEntity: Name: NameFull: Bayliss R – PersonEntity: Name: NameFull: Gileadi O – PersonEntity: Name: NameFull: von Delft F IsPartOfRelationships: – BibEntity: Dates: – D: 27 M: 10 Text: 2025 Oct 27 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 2374-7943 Numbering: – Type: volume Value: 11 – Type: issue Value: 12 Titles: – TitleFull: ACS central science Type: main |
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