View in EDS

Mass spectrometry footprinting reveals how kinetic stabilizers counteract transthyretin dynamics altered by pathogenic mutations.

Saved in:
Bibliographic Details
Title: Mass spectrometry footprinting reveals how kinetic stabilizers counteract transthyretin dynamics altered by pathogenic mutations.
Authors: Pinheiro F; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain., Kant R; Department of Chemistry, Washington University, St. Louis, MO 63130., Chemuru S; Department of Chemistry, Washington University, St. Louis, MO 63130., Varejão N; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain., Velázquez-Campoy A; Faculty of Sciences, Department of Biochemistry and Molecular and Cellular Biology, Institute of Biocomputation and Physics of Complex Systems, Universidad de Zaragoza, Zaragoza 50018, Spain.; Institute for Health Research Aragon (Instituto de Investigación Sanitaria Aragón), Zaragoza 50009, Spain.; Networking Biomedical Research Centre in Liver and Digestive Diseases, Madrid 28029, Spain.; Department of Biochemistry and Molecular and Cell Biology, University of Zaragoza, Zaragoza 50009, Spain., Reverter D; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain., Pallarès I; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain., Gross ML; Department of Chemistry, Washington University, St. Louis, MO 63130., Ventura S; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain.; Institut d'Investigació i Innovació Parc Taulí - Catalan Network of Research Centers, Sabadell 08208, Spain.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jan 06; Vol. 123 (1), pp. e2519908122. Date of Electronic Publication: 2025 Dec 31.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41474749
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Mass spectrometry footprinting reveals how kinetic stabilizers counteract transthyretin dynamics altered by pathogenic mutations.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Pinheiro+F%22">Pinheiro F</searchLink>; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain.<br /><searchLink fieldCode="AU" term="%22Kant+R%22">Kant R</searchLink>; Department of Chemistry, Washington University, St. Louis, MO 63130.<br /><searchLink fieldCode="AU" term="%22Chemuru+S%22">Chemuru S</searchLink>; Department of Chemistry, Washington University, St. Louis, MO 63130.<br /><searchLink fieldCode="AU" term="%22Varejão+N%22">Varejão N</searchLink>; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain.<br /><searchLink fieldCode="AU" term="%22Velázquez-Campoy+A%22">Velázquez-Campoy A</searchLink>; Faculty of Sciences, Department of Biochemistry and Molecular and Cellular Biology, Institute of Biocomputation and Physics of Complex Systems, Universidad de Zaragoza, Zaragoza 50018, Spain.; Institute for Health Research Aragon (Instituto de Investigación Sanitaria Aragón), Zaragoza 50009, Spain.; Networking Biomedical Research Centre in Liver and Digestive Diseases, Madrid 28029, Spain.; Department of Biochemistry and Molecular and Cell Biology, University of Zaragoza, Zaragoza 50009, Spain.<br /><searchLink fieldCode="AU" term="%22Reverter+D%22">Reverter D</searchLink>; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain.<br /><searchLink fieldCode="AU" term="%22Pallarès+I%22">Pallarès I</searchLink>; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain.<br /><searchLink fieldCode="AU" term="%22Gross+ML%22">Gross ML</searchLink>; Department of Chemistry, Washington University, St. Louis, MO 63130.<br /><searchLink fieldCode="AU" term="%22Ventura+S%22">Ventura S</searchLink>; Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona 08193, Spain.; Institut d'Investigació i Innovació Parc Taulí - Catalan Network of Research Centers, Sabadell 08208, Spain.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2026 Jan 06; Vol. 123 (1), pp. e2519908122. <i>Date of Electronic Publication: </i>2025 Dec 31.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41474749
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1073/pnas.2519908122
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e2519908122
    Titles:
      – TitleFull: Mass spectrometry footprinting reveals how kinetic stabilizers counteract transthyretin dynamics altered by pathogenic mutations.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Pinheiro F
      – PersonEntity:
          Name:
            NameFull: Kant R
      – PersonEntity:
          Name:
            NameFull: Chemuru S
      – PersonEntity:
          Name:
            NameFull: Varejão N
      – PersonEntity:
          Name:
            NameFull: Velázquez-Campoy A
      – PersonEntity:
          Name:
            NameFull: Reverter D
      – PersonEntity:
          Name:
            NameFull: Pallarès I
      – PersonEntity:
          Name:
            NameFull: Gross ML
      – PersonEntity:
          Name:
            NameFull: Ventura S
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 06
              M: 01
              Text: 2026 Jan 06
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1091-6490
          Numbering:
            – Type: volume
              Value: 123
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Proceedings of the National Academy of Sciences of the United States of America
              Type: main
ResultId 1