Native C3 is activated without proteolytic cleavage by transformation to C3(H2O) on phospholipid-scrambled cell membranes.
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| Title: | Native C3 is activated without proteolytic cleavage by transformation to C3(H |
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| Authors: | Eikrem D; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Manivel VA; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Whittaker J; Department of Molecular Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden., Hamad OA; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Mohlin C; Linnaeus Centre for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden., Adler A; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Dührkop C; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Ebert R; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Teramura Y; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Cellular and Molecular Biotechnology Research Institute (CMB), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.; Master's/Doctoral Program in Life Science Innovation (T-LSI), University of Tsukuba, Tsukuba, Ibaraki, Japan., Ekdahl KN; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Linnaeus Centre for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden., Fromell K; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Nilsson B; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. |
| Source: | Frontiers in immunology [Front Immunol] 2025 Dec 16; Vol. 16, pp. 1729532. Date of Electronic Publication: 2025 Dec 16 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1729532 |
