| Authors: |
Zhang M; Department of Biostatistics and Data Science, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Brown MR; Human Genetics Center, Department of Epidemiology, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Noordam R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Health Campus the Hague/Public Health and Primary Care, Leiden University Medical Center, the Hague, the Netherlands., Nagarajan P; Division of Sleep and Circadian Disorders, Department of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA, USA., Guo B; Department of Biostatistics and Data Science, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Lee S; McGovern Medical School, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Schwander K; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, Saint Louis, MO, USA., Wang W; Department of Human Genetics, Leiden University Medical Center, Leiden, South Holland, the Netherlands., Westerman K; Clinical and Translational Epidemiology Unit, Mongan Institute, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., O'Connell JR; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Ammous F; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Argoty-Pantoja AD; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Bartz TM; Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington, Seattle, WA, USA., Batini C; Genetic Epidemiology Group, Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK., Boua PR; Clinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Santé, Ouagadougou, Kadiogo, Burkina Faso.; Sydney Brenner Institute for Molecular Bioscience (SBIMB), University of the Witwatersrand, Johannesburg, Gauteng, South Africa.; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Cordell HJ; Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Díez-Ahijado L; Unit of Genomics of Complex Disease, Institut de Recerca Sant Pau (IR SANT PAU), Barcelona, Catalonia, Spain., Dimitrov L; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Do AN; Center for Biostatistics and Data Science, Institute for Informatics, Data Science, and Biostatistics, Washington University in St. Louis, St. Louis, MO, USA., Du J; Department of Biostatistics, University of North Carolina at Chapel Hill, NC., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, Saint Louis, MO, USA., Giri A; Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA.; VA Tennessee Valley Healthcare System (626), Nashville, TN, USA., Giulianini F; Division of Preventive Medicine, Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gudmundsdottir V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Guo X; Genomic Outcomes, Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Harris SE; Lothian Birth Cohorts, Psychology, The University of Edinburgh, Edinburgh, UK., Hasbani NR; Department of Epidemiology, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Herold JM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Hikino K; Laboratory for Pharmacogenomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Hsu FC; Division of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Jackson AU; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Kho M; Graduate School of Data Science, Seoul National University, South Korea., Kraja AT; University of Mississippi Medical Center, Jackson, MS, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Department of Clinical Chemistry, Tampere University, Tampere, Finland., Meirhaeghe A; Lille University; Lille University Hospital; INSERM U1167 - RID-AGE; Institut Pasteur de Lille, University of Lille, Inserm, Institut Pasteur de Lille, Lille, France., Muntaner M; Lille University; Lille University Hospital; INSERM U1167 - RID-AGE; Institut Pasteur de Lille, University of Lille, Inserm, Institut Pasteur de Lille, Lille, France., Nakatochi M; Public Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan., Nardone GG; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Nutile T; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy., Palmer ND; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Pecori A; Institute for Maternal and Child Health, I.R.C.C.S. 'Burlo Garofolo', Trieste, Italy., Rao VS; Graduate Program in Life Sciences, University of Maryland, Baltimore, Baltimore, MD, USA., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Sanghvi MM; William Harvey Research Institute, Centre for Pharmacology and Precision Medicine, Queen Mary University of London, London, UK.; Barts Heart Centre, Barts Health NHS Trust, London, UK., Santin A; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, I.R.C.C.S. 'Burlo Garofolo', Trieste, Italy., Shen B; National Institute on Aging, Bethesda, MD, USA., Stringham HM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Takeuchi F; Department of Bioinformatics, National Institute of Global Health and Medicine, Japan Institute for Health Security, Shinjuku-ku, Tokyo, Japan., Tan YA; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore, Singapore., Tang J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Thériault S; Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Quebec City, Quebec, Canada., Trofimova O; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland., Trompet S; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China., Wang Z; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Wang Y; Gillings School of Global Public Health, Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Ware EB; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Weiss S; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Wickremasinghe AR; Faculty of Medicine, University of Kelaniya, Kelaniya, Ragama, Sri Lanka., Yu C; School of Public Health and Preventive Medicine, Monash University, Victoria 3004 Australia., Zhu W; Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Ansari MAY; Department of Data Science, University of Mississippi Medical Center, Jackson, MS, USA., Anugu P; Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS, USA., Banas B; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Barr RG; General Medicine, Medicine, Columbia University Medical Center, New York, NY, USA., Basnet TB; Tennessee Valley Healthcare System, Nashville VA Medical Center, Nashville, TN, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.; Department of Nephrology, Hospital Traunstein, Traunstein, Germany., Breyer M; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Broeckel U; Section of Genomic Pediatrics, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Bryant L; Department of Respiratory Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK., Cade B; Division of Sleep and Circadian Disorders, Department of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Department of Medicine, Harvard Medical School, Boston, MA, USA., Camarda S; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Cennamo P; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy., Checkley W; Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD, USA., Chee ML; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore, Singapore., Chen G; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Coley K; Genetic Epidemiology Group, Department of Population Health Sciences, University of Leicester, Leicester, UK., Collins SD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., de Borst MH; Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., de Las Fuentes L; Center for Biostatistics and Data Science, Institute for Informatics, Data Science, and Biostatistics, Washington University in St. Louis, St. Louis, MO, USA.; Cardiovascular Division, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Deary IJ; Lothian Birth Cohorts, Psychology, The University of Edinburgh, Edinburgh, UK., Dupont CT; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Enzinger C; Division of General Neurology, Department of Neurology, Medical University of Graz, Graz, Austria.; Division of Neuroradiology, Interventional and Vascular Radiology, Department of Radiology, Medical University of Graz, Graz, Austria., Faquih T; Division of Sleep and Circadian Disorders, Department of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Department of Medicine, Harvard Medical School, Boston, MA, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Silva LF; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Gauthier V; Lille University; Lille University Hospital; INSERM U1167 - RID-AGE; Institut Pasteur de Lille, University of Lille, Inserm, Institut Pasteur de Lille, Lille, France., Gepner AD; Cardiovascular Medicine, Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA., Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Centre for Neurodegenerative Diseases, Site Rostock/Greifswald, Greifswald, Germany., Graff M; Gillings School of Global Public Health, Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gu CC; Center for Biostatistics and Data Science, Institute for Informatics, Data Science, and Biostatistics, Washington University in St. Louis, St. Louis, MO, USA., He J; Department of Epidemiology, O'Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USA., Heikkinen S; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland., Hidalgo B; Epidemiology, UAB School of Public Health, Birmingham, Alabama, USA., Highland HM; Gillings School of Global Public Health, Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Hixson JE; Department of Epidemiology, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Hood MM; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Hunt SC; Epidemiology, Internal Medicine, University of Utah, Salt Lake City, UT, USA., Irvin MR; Epidemiology, UAB School of Public Health, Birmingham, Alabama, USA., Isono M; Department of Gene Diagnostics and Therapeutics, National Institute of Global Health and Medicine, Japan Institute for Health Security, Shinjuku-ku, Tokyo, Japan., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Department of Clinical Physiology, Tampere University, Tampere, Finland., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Karvonen-Gutierrez CA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kasturiratne A; Faculty of Medicine, University of Kelaniya, Kelaniya, Ragama, Sri Lanka., Katsuya T; Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Suita-shi, Osaka, Japan., Kaufman JD; Epidemiology, University of Washington Seattle, Seattle, WA, USA., Koistinen HA; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; University of Helsinki, Research Programs Unit, Clinical and Molecular Metabolism; Department of Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Komulainen P; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Krämer BK; Fifth Department of Medicine (Nephrology/Endocrinology/Rheumatology/Pneumology), University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.; European Center for Angioscience ECAS, Medical Faculty Mannheim of the University of Heidelberg, Mannheim, Germany., Launer LJ; Intramural Research Program, Laboratory of Epidemiology and Population Sciences, Intramural Research Program, Laboratory of Epidemiology and Population Sciences., Leonard H; NIH Center for Alzheimer's and Related Dementias, Bethesda, MD, USA., Levy D; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Liu J; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore, Singapore., Marques-Vidal P; Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Martinez-Perez A; Unit of Genomics of Complex Disease, Institut de Recerca Sant Pau (IR SANT PAU), Barcelona, Catalonia, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain., Matsuda K; Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan., McNeil JJ; School of Public Health and Preventive Medicine, Monash University, Victoria 3004 Australia., Milaneschi Y; Psychiatry, Amsterdam, the Netherlands., Miranda JJ; CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.; Sydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Sydney, Australia., Morrison JL; Division of Biostatistics, Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA., Nalls M; NIH Center for Alzheimer's and Related Dementias, Bethesda, MD, USA., Ng MC; Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Norris JM; Department of Epidemiology, Colorado School of Public Health, Aurora, CO, USA., Oravilahti A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland., Patki A; Biostatistics, UAB School of Public Health, Birmingham, Alabama, USA., Petty LE; Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Pianigiani G; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, I.R.C.C.S. 'Burlo Garofolo', Trieste, Italy., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Raitakari OT; Centre for Population Health Research, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, Department of Clinical Physiology and Nuclear Medicine, University of Turku, Turku, Finland., Ramsay M; Sydney Brenner Institute for Molecular Bioscience (SBIMB), University of the Witwatersrand, Johannesburg, Gauteng, South Africa., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA., Risch L; Institute of Laboratory Medicine, Faculty of Medical Sciences, Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.; Center of Laboratory Medicine, University Institute of Clinical Chemistry, University of Bern, Bern, Switzerland., Risch M; Dr. Risch Medical Laboratory, Vaduz, Liechtenstein.; Zentrallabor, Kantonsspital Graubünden, Chur, Switzerland., Ruggiero D; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy., Ruiz-Narvaez EA; Department of Nutritional Sciences, University of Michigan, Ann Arbor, MI, USA., Russ TC; Lothian Birth Cohorts, Psychology, The University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, Psychology, The University of Edinburgh, Edinburgh, UK.; Division of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore, Singapore., Vaitinadin NS; Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Scott LJ; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Singh S; Sydney Brenner Institute for Molecular Bioscience (SBIMB), University of the Witwatersrand, Johannesburg, Gauteng, South Africa.; Division of Human Genetics, School of Pathology, University of the Witwatersrand, Johannesburg, Gauteng, South Africa., Sitlani CM; Cardiovascular Health Research Unit, General Internal Medicine, Department of Medicine, University of Washington, Seattle, WA, USA., Smit RAJ; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Smith JA; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Sun Q; Department of Biostatistics, University of North Carolina at Chapel Hill, NC., Tai ES; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore, Singapore., Taylor KD; Genomic Outcomes, Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Tesolin P; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, I.R.C.C.S. 'Burlo Garofolo', Trieste, Italy., Tham YC; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore, Singapore.; Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore, Singapore., Tinashe C; Channing Division of Network Medicine, Department of Medicine, Brigham Hospital, Harvard University, Boston, Massachusetts, USA., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore, Singapore.; Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington, DC, USA., Vaucher J; Internal Medicine, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.; Division of Internal Medicine, Department of Medicine and Specialties, Fribourg Hospital and University of Fribourg, Fribourg, Switzerland., Völker U; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Wang C; School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hebei, China., Wilson OD; Tennessee Valley Healthcare System, Nashville VA Medical Center, Nashville, TN, USA.; Division of Hypertension and Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Wong TY; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore, Singapore.; Tsinghua Medicine, Tsinghua University, Haidian District, Beijing, China., Xu J; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Yamamoto K; Department of Medical Biochemistry, Kurume University School of Medicine, Kurume, Fukuoka, Japan., Yao J; Genomic Outcomes, Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Yokota M; Kurume University School of Medicine, Kurume, Fukuoka, Japan., Young KL; Gillings School of Global Public Health, Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Zimmermann ME; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Amouyel P; Lille University; Lille University Hospital; INSERM U1167 - RID-AGE; Institut Pasteur de Lille, University of Lille, Inserm, Institut Pasteur de Lille, Lille, France., Below JE; Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland., Bernabe-Ortiz A; CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru., Bierut L; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA., Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Bowden DW; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Brandenburg JT; Sydney Brenner Institute for Molecular Bioscience (SBIMB), University of the Witwatersrand, Johannesburg, Gauteng, South Africa.; Strengthening Oncology Services Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Gauteng, South Africa., Chasman DI; Division of Preventive Medicine, Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore, Singapore.; Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore, Singapore., Ciullo M; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Naples, Italy., Concas MP; Institute for Maternal and Child Health, I.R.C.C.S. 'Burlo Garofolo', Trieste, Italy., Conen D; Population Health Research Institute, McMaster University, Hamilton, ON, Canada., Cox SR; Lothian Birth Cohorts, Psychology, The University of Edinburgh, Edinburgh, UK., Dauchet L; Lille University; Lille University Hospital; INSERM U1167 - RID-AGE; Institut Pasteur de Lille, University of Lille, Inserm, Institut Pasteur de Lille, Lille, France., de Silva HJ; Faculty of Medicine, University of Kelaniya, Kelaniya, Ragama, Sri Lanka., Dörr M; Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Edwards TL; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; VA Tennessee Valley Healthcare System (626), Nashville, TN, USA., Fox ER; Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS, USA., Franceschini N; Department of Epidemiology, University of North Carolina at Chapel Hill, NC.; Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, NC., Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Girotto G; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, I.R.C.C.S. 'Burlo Garofolo', Trieste, Italy., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Harlow SD; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Heid IM; national Institute of Global Health and Medicine, University of Regensburg, Regensburg, Germany., Hung AM; Tennessee Valley Healthcare System, Nashville VA Medical Center, Nashville, TN, USA.; Division of Hypertension and Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Ichihara S; Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan., Jaquish CE; Division of Cardiovascular Science, Epidemiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., John C; Genetic Epidemiology Group, Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Leicester British Heart Foundation Centre of Research Excellence, Leicester, UK., Jonas JB; Privatpraxis Prof Jonas und Dr Panda-Jonas, Heidelberg, Germany, Germany.; Rothschild Foundation Hospital, Paris, France., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Kato N; Department of Gene Diagnostics and Therapeutics, National Institute of Global Health and Medicine, Japan Institute for Health Security, Shinjuku-ku, Tokyo, Japan., Keavney BD; Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Heart Institute, Manchester University NHS Foundation Trust, Manchester, UK., Kelly TN; Division of Nephrology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Lacaze P; School of Public Health and Preventive Medicine, Monash University, Victoria 3004 Australia., Lakka T; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Lee S; Graduate School of Data Science, Seoul National University, South Korea., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Department of Clinical Chemistry, Tampere University, Tampere, Finland., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., North KE; Gillings School of Global Public Health, Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Penninx B; Psychiatry, Amsterdam, the Netherlands., Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, Saint Louis, MO, USA., Psaty BM; Cardiovascular Health Research Unit, General Internal Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA., Redline S; Division of Sleep and Circadian Disorders, Department of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Department of Medicine, Harvard Medical School, Boston, MA, USA., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Rotter JI; Genomic Outcomes, Pediatrics, The Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Sabater-Lleal M; Unit of Genomics of Complex Disease, Institut de Recerca Sant Pau (IR SANT PAU), Barcelona, Catalonia, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain.; Cardiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Schmidt H; Division of Genetic Epidemiology, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria., Sim X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore, Singapore., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Spedicati B; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, I.R.C.C.S. 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