Shared genetic architecture of brain age gap across 30 cohorts worldwide.

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Bibliographic Details
Title: Shared genetic architecture of brain age gap across 30 cohorts worldwide.
Authors: Baltramonaityte V; Department of Psychology, University of Bath, Bath, United Kingdom., Jawinski P; Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany., Staginnus M; Department of Psychology, University of Bath, Bath, United Kingdom., Shahisavandi M; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands., Kovacs BZ; Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands., Schuurmans IK; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands., Constantinides C; Department of Psychology, University of Bath, Bath, United Kingdom., Hariri AR; Department of Psychology & Neuroscience, Duke University, Durham, United States., Teumer A; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Rodrigue AL; Department of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Boston, United States., Tsuchida A; GIN, IMN UMR 5293, CEA, CNRS, Université de Bordeaux, Bordeaux, France., Manzouri A; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Stockholm, Sweden.; Department of Psychology, Stockholm University, Stockholm, Sweden.; Department of Clinical Psychology and Psychotherapy, Babeș-Bolyai University, Cluj-Napoca, Romania., Karuk A; FIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Fürtjes AE; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom.; Lothian Birth Cohorts, Edinburgh Futures Institute, University of Edinburgh, Edinburgh, United Kingdom., Lella A; Clinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, University of California Irvine, Irvine, United States., Knodt AR; Department of Psychology & Neuroscience, Duke University, Durham, United States., Jüllig A; Department of Experimental Psychology and Cognition Research, Justus-Liebig-University, Gießen, Germany., Caspi A; Department of Psychology & Neuroscience, Duke University, Durham, United States.; Institute of Psychiatry, Psychology, & Neuroscience, King's College London, London, England., Crespo-Facorro B; Hospital Universitario Virgen del Rocio, IBIS-CSIC, CIBERSAM, Sevilla, Spain., Penninx BW; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Lavebratt C; Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Stockholm, Sweden., Lochner C; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, Stellenbosch University, Tygerberg, South Africa., Yasuda CL; Department of Neurology, State University of Campinas, Campinas, Brazil.; Brazilian Institute of Neuroscience and Neurotechnology, Brazil., Alnæs D; Department of Psychology, University of Oslo, Oslo, Norway.; Center for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Stein DJ; Department of Psychiatry and Mental Health, Neuroscience Institute, University of Cape Town, Cape Town, South Africa.; South Africa Medical Research Council Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, University of Cape Town, Cape Town, South Africa., Mathalon DH; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, United States., Glahn DC; Department of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Boston, United States.; Department of Psychiatry, Harvard Medical School, Boston, United States., Klose D; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Kiltschewskij DJ; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, Australia.; Precision Medicine Research Program, Hunter Medical Research Institute, Newcastle, Australia., Pomarol-Clotet E; FIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Bruxel EM; Brazilian Institute of Neuroscience and Neurotechnology, Brazil.; Department of Medical Genetics and Genomic Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Crivello F; GIN, IMN UMR 5293, CEA, CNRS, Université de Bordeaux, Bordeaux, France., Cendes F; Department of Neurology, State University of Campinas, Campinas, Brazil., Davies G; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom.; School of Philosophy, Psychology & Language Sciences, The University of Edinburgh, Edinburgh, United Kingdom., Salum GA; Department of Psychiatry and Legal Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Child Mind Institute, New York, United States., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Center of Neurodegenerative Diseases (DZNE), Site Rostock/Greifswald, Greifswald, Germany., Zar HJ; Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.; South Africa Medical Research Council Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa., Tiemeier H; Harvard T.H. Chan School of Public Health, Department of Behavioral and Social Sciences, Boston, United States.; Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands., Völzke H; University Medicine Greifswald, Institute for Community Medicine, Greifswald, Germany., Lemaître H; GIN, IMN UMR 5293, CEA, CNRS, Université de Bordeaux, Bordeaux, France., Lopes-Cendes I; Brazilian Institute of Neuroscience and Neurotechnology, Brazil.; Department of Medical Genetics and Genomic Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Aventurato ÍK; Department of Neurology, State University of Campinas, Campinas, Brazil., Shin J; Centre de recherche CHU Sainte-Justine and University of Montreal Montréal Canada., Turner JA; Department of Psychiatry and Behavioral Health, Wexner Medical Center, Ohio State University, Columbus, United States., Wardlaw JM; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, United Kingdom.; UK Dementia Research Institute Centre, University of Edinburgh, Edinburgh, United Kingdom., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, University of Texas of the Rio Grande Valley, Brownsville, TX, United States., Ipser JC; Department of Psychiatry and Mental Health, Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Ford JM; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, California, United States.; Dept of Veterans Affairs, San Francisco, California, United States., Sim K; West Region, Institute of Mental Health, Singapore, Singapore., Sugden K; Department of Psychology & Neuroscience, Duke University, Durham, United States., Wittfeld K; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Salontaji K; Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands., Månsson KN; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Stockholm, Sweden.; Department of Clinical Psychology and Psychotherapy, Babeș-Bolyai University, Cluj-Napoca, Romania., Hong LE; Department of Psychiatry, The University of Texas Health Science Center, Houston, United States., Westlye LT; Department of Psychology, University of Oslo, Oslo, Norway.; Center for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Schmaal L; Centre for Youth Mental Health, University of Melbourne, Melbourne, Australia.; Orygen, The National Centre of Excellence in Youth Mental Health, Parkville, Australia., Ito LT; Discipline of Molecular Biology - Department of Biochemistry, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil., Scárdua-Silva L; Department of Neurology, State University of Campinas, Campinas, Brazil.; Brazilian Institute of Neuroscience and Neurotechnology, Brazil., Santoro ML; Discipline of Molecular Biology - Department of Biochemistry, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil., Alemany-Navarro M; Translational Psychiatry Group, Instituto de Biomedicina de Sevilla (IBiS)-CSIC, Seville, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Bastin ME; Institute of Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, United Kingdom., Mufford MS; Division of Human Genetics, University of the Witwatersrand, Johannesburg, South Africa.; Department of Psychiatry and Mental Health, Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Green MJ; School of Clinical Medicine, University of New South Wales, Sydney, Australia., Cairns MJ; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Newcastle, Australia.; Precision Medicine Research Program, Hunter Medical Research Institute, Newcastle, Australia., Parker N; Center for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., McGregor NW; Human and Systems Genetics Working Group, Department of Genetics, Stellenbosch University, Stellenbosch, South Africa., Andreassen OA; Center for Precision Psychiatry, Division of Mental Health and Addiction, University of Oslo and Oslo University Hospital, Oslo, Norway., Gruber O; Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University, Heidelberg, Germany., Watkeys OJ; School of Clinical Medicine, Discipline of Psychiatry and Mental Health, University of New South Wales, Randwick, Australia., Pan PM; Laboratory of Integrative Neurosciences (LiNC), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil., Kochunov P; Department of Psychiatry, The University of Texas Health Science Center, Houston, United States., Chew QH; West Region, Institute of Mental Health, Singapore, Singapore., Romero-Garcia R; Department of Medical Physiology and Biophysics, Seville, Spain.; Instituto de Biomedicina de Sevilla (IBiS) HUVR/CSIC, CIBERSAM, ISCIII, Seville, Span., Salvador R; FIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Theodore R; Dunedin Multidisciplinary Health and Development Research Unit, University of Otago, Dunedin, New Zealand., Poulton R; Dunedin Multidisciplinary Health and Development Research Unit, University of Otago, Dunedin, New Zealand., Bülow R; Institute for Diagnostic Radiology and Neuroradiology, Greifswald, Germany., Bressan RA; Laboratory of Integrative Neurosciences (LiNC), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.; Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil., Muetzel RL; Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Markett S; Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany., Defina S; Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands., Koopowitz SM; Department of Psychiatry and Mental Health, Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Dahan S; Clinical Neuroimaging Laboratory, Galway Neuroscience Center, College of Medicine, Nursing & Health Sciences, University of Galway, Galway, Ireland., Cox SR; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom.; Lothian Birth Cohorts, Edinburgh Futures Institute, University of Edinburgh, Edinburgh, United Kingdom., Belangero S; Laboratory of Integrative Neurosciences (LiNC), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.; Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.; Graduate Program in Structural and Functional Biology, Universidade Federal de São Paulo, São Paulo, Brazil., Vijayakumar Kamalakannan SM; Clinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, University of California Irvine, Irvine, United States., Thomopoulos SI; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, United States., Frenzel S; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Moffitt TE; Department of Psychology & Neuroscience, Duke University, Durham, United States.; Institute of Psychiatry, Psychology, & Neuroscience, King's College London, London, England., van Erp TG; Clinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, University of California Irvine, Irvine, United States.; Center for the Neurobiology of Learning and Memory, University of California Irvine, Irvine, United States., Furmark T; Department of Psychology, Uppsala University, Uppsala, Sweden., Paus T; Departments of Psychiatry and Neuroscience, University of Montreal, Montreal, Canada., Völker U; Department Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Calhoun VD; Tri-institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State, Georgia Tech, Emory, Atlanta, United States., Quidé Y; NeuroRecovery Research hub, School of Psychology, UNSW Sydney, Sydney, Australia.; Centre for Pain IMPACT, Neuroscience Research Australia, Randwick, Australia., Lee Y; Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University, Heidelberg, Germany., Milaneschi Y; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Mental Health Program, Amsterdam Public Health, Amsterdam, The Netherlands.; Complex Trait Genetics program, Amsterdam Neuroscience, Amsterdam, The Netherlands., Pausova Z; Centre de recherche CHU Sainte-Justine and University of Montreal Montréal Canada., Thompson PM; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, United States., Han LK; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Mood, Anxiety, Psychosis, Sleep & Stress program, Amsterdam, The Netherlands.; Amsterdam Public Health, Mental Health program, Amsterdam, The Netherlands., Pingault JB; Department of Clinical, Educational and Health Psychology London, University College London, United Kingdom., Cole JH; Hawkes Institute, Department of Computer Science, University College London, London, United Kingdom., Cecil CA; Department of Child and Adolescent Psychiatry/Psychology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands., Medland SE; Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia.; School of Psychology, University of Queensland, Brisbane, Australia., Dima D; Department of Psychology and Neuroscience, City St George's, University of London, London, United Kingdom.; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Walton E; Department of Psychology, University of Bath, Bath, United Kingdom.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Dec 27. Date of Electronic Publication: 2025 Dec 27.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
DOI:10.64898/2025.12.23.25342890