A Placebo-Controlled Exploratory Trial of Sirolimus for Tocilizumab-Resistant Idiopathic Multicentric Castleman Disease: Early Termination and Long-Term Extension Results Based on Descriptive Results From Two Patients.
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| Title: | A Placebo-Controlled Exploratory Trial of Sirolimus for Tocilizumab-Resistant Idiopathic Multicentric Castleman Disease: Early Termination and Long-Term Extension Results Based on Descriptive Results From Two Patients. |
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| Authors: | Koga T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN., Sumiyoshi R; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN., Shimizu T; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN., Hosogaya N; Clinical Research Center, Nagasaki University Hospital, Nagasaki, JPN., Fukushima C; Clinical Research Center, Nagasaki University Hospital, Nagasaki, JPN., Yamamoto H; Clinical Research Center, Nagasaki University Hospital, Nagasaki, JPN., Yoshifuji H; Department of Rheumatology and Clinical Immunology, Kyoto University, Kyoto, JPN., Higa S; Department of Internal Medicine, Division of Rheumatology, Daini Osaka Police Hospital, Osaka, JPN., Kawakami A; Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN. |
| Source: | Cureus [Cureus] 2025 Dec 01; Vol. 17 (12), pp. e98233. Date of Electronic Publication: 2025 Dec 01 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2168-8184 |
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| DOI: | 10.7759/cureus.98233 |
