Bacterial ubiquitin ligase engineered for small molecule and protein target identification.
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| Title: | Bacterial ubiquitin ligase engineered for small molecule and protein target identification. |
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| Authors: | Ye JS; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Majumdar A; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Park BC; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Black MH; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Hsieh TS; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Osinski A; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Servage KA; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Kulkarni K; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Naidoo J; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Alto NM; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Stratton MM; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, MA, 01003, USA., Alfandari D; Department of Veterinary and Animal Sciences, University of Massachusetts Amherst, Amherst, MA, 01003, USA., Ready JM; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Pawłowski K; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Tomchick DR; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA., Tagliabracci VS; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. vincent.tagliabracci@utsouthwestern.edu.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. vincent.tagliabracci@utsouthwestern.edu.; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. vincent.tagliabracci@utsouthwestern.edu.; Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. vincent.tagliabracci@utsouthwestern.edu. |
| Source: | The EMBO journal [EMBO J] 2026 Feb; Vol. 45 (3), pp. 1024-1050. Date of Electronic Publication: 2026 Jan 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-025-00665-0 |
