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Decoding the long-term safety of anti-CGRP (receptor) mAbs: a meta-analysis and systematic review.

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Title: Decoding the long-term safety of anti-CGRP (receptor) mAbs: a meta-analysis and systematic review.
Authors: Hoehne CL; Department of Neurology, Charité Universitätsmedizin Berlin, Corporate member of Humboldt University and Frei Universität Berlin, Charitéplatz 1, Bonhoefferweg 3, 10117, Berlin, Germany., Overeem LH; Department of Neurology, Charité Universitätsmedizin Berlin, Corporate member of Humboldt University and Frei Universität Berlin, Charitéplatz 1, Bonhoefferweg 3, 10117, Berlin, Germany., Sanchez-Del-Rio M; Department of Neurology, Clínica Universidad de Navarra, Calle Marquesado de Santa Marta, 1, Madrid, 28027, Spain., Deligianni C; First Department of Neurology, Aeginition Hospital, Medical School National and Kapodistrian University of Athens, Athens, Greece.; Neurology Department, Athens Naval Hospital, Athens, Greece., Gil-Gouveia R; Neurology Department, Hospital da Luz, Lisboa, Portugal.; Center for Interdisciplinary Research in Health, Universidade Católica Portuguesa, Lisboa, Portugal., Versijpt J; Department of Neurology, Universitair Ziekenhuis Brussel, Brussels, Belgium.; Neuroprotection and Neuromodulation Research Group, Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium., Amin FM; Department of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark., Lampl C; Department of Neurology, Krankenhaus Barmherzige Brüder, Linz, Austria., Ryliskiene K; Neurology and Neurosurgery Clinic, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania., Tronvik E; NorHead, Norwegian Headache Research Centre, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway., Coppola G; Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino ICOT, Latina, Italy., Holland PR; Headache Group, Wolfson Sensory Pain and Regeneration Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., MaassenVanDenBrink A; Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, PO Box 2040, Rotterdam, CA 3000, The Netherlands., Martelletti P; School of Health, Unitelma Sapienza University of Rome, 00161, Rome, Italy., Reuter U; Department of Neurology, Charité Universitätsmedizin Berlin, Corporate member of Humboldt University and Frei Universität Berlin, Charitéplatz 1, Bonhoefferweg 3, 10117, Berlin, Germany. uwe.reuter@charite.de.
Corporate Authors: European Headache Federation, EHF
Source: The journal of headache and pain [J Headache Pain] 2026 Jan 03; Vol. 27 (1), pp. 10. Date of Electronic Publication: 2026 Jan 03.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Decoding the long-term safety of anti-CGRP (receptor) mAbs: a meta-analysis and systematic review.
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  Data: <searchLink fieldCode="AU" term="%22Hoehne+CL%22">Hoehne CL</searchLink>; Department of Neurology, Charité Universitätsmedizin Berlin, Corporate member of Humboldt University and Frei Universität Berlin, Charitéplatz 1, Bonhoefferweg 3, 10117, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Overeem+LH%22">Overeem LH</searchLink>; Department of Neurology, Charité Universitätsmedizin Berlin, Corporate member of Humboldt University and Frei Universität Berlin, Charitéplatz 1, Bonhoefferweg 3, 10117, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Sanchez-Del-Rio+M%22">Sanchez-Del-Rio M</searchLink>; Department of Neurology, Clínica Universidad de Navarra, Calle Marquesado de Santa Marta, 1, Madrid, 28027, Spain.<br /><searchLink fieldCode="AU" term="%22Deligianni+C%22">Deligianni C</searchLink>; First Department of Neurology, Aeginition Hospital, Medical School National and Kapodistrian University of Athens, Athens, Greece.; Neurology Department, Athens Naval Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Gil-Gouveia+R%22">Gil-Gouveia R</searchLink>; Neurology Department, Hospital da Luz, Lisboa, Portugal.; Center for Interdisciplinary Research in Health, Universidade Católica Portuguesa, Lisboa, Portugal.<br /><searchLink fieldCode="AU" term="%22Versijpt+J%22">Versijpt J</searchLink>; Department of Neurology, Universitair Ziekenhuis Brussel, Brussels, Belgium.; Neuroprotection and Neuromodulation Research Group, Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Amin+FM%22">Amin FM</searchLink>; Department of Neurology, Danish Headache Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lampl+C%22">Lampl C</searchLink>; Department of Neurology, Krankenhaus Barmherzige Brüder, Linz, Austria.<br /><searchLink fieldCode="AU" term="%22Ryliskiene+K%22">Ryliskiene K</searchLink>; Neurology and Neurosurgery Clinic, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.<br /><searchLink fieldCode="AU" term="%22Tronvik+E%22">Tronvik E</searchLink>; NorHead, Norwegian Headache Research Centre, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Coppola+G%22">Coppola G</searchLink>; Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino ICOT, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Holland+PR%22">Holland PR</searchLink>; Headache Group, Wolfson Sensory Pain and Regeneration Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22MaassenVanDenBrink+A%22">MaassenVanDenBrink A</searchLink>; Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, PO Box 2040, Rotterdam, CA 3000, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Martelletti+P%22">Martelletti P</searchLink>; School of Health, Unitelma Sapienza University of Rome, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Reuter+U%22">Reuter U</searchLink>; Department of Neurology, Charité Universitätsmedizin Berlin, Corporate member of Humboldt University and Frei Universität Berlin, Charitéplatz 1, Bonhoefferweg 3, 10117, Berlin, Germany. uwe.reuter@charite.de.
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  Data: <searchLink fieldCode="CA" term="%22European+Headache+Federation%2C+EHF%22">European Headache Federation, EHF</searchLink>
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