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Melatonin suppresses glycolysis and coordinately disrupts DNA repair via targeting the YAP1-NAMPT signaling in breast cancer.

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Title: Melatonin suppresses glycolysis and coordinately disrupts DNA repair via targeting the YAP1-NAMPT signaling in breast cancer.
Authors: Lai YW; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Chu CY; CRISPR Gene Targeting Core Lab, Taipei Medical University, Taipei, 110, Taiwan., Liu ZW; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan., Lu HY; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Division of Cardiovascular Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taiwan., Lee CC; Department of Food Engineering, Faculty of Engineering and Natural Sciences, Istanbul Sabahattin Zaim University, Istanbul, 343, Türkiye; Department of Food Technology and Nutrition, Faculty of Technologies, Klaipėdos valstybinė kolegija, Higher Education Institution, Lithuania., Lin MH; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan. Electronic address: mhl00001@tmu.edu.tw., Lin CW; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, 807, Taiwan. Electronic address: cwlin@tmu.edu.tw.
Source: Chemico-biological interactions [Chem Biol Interact] 2026 Feb 11; Vol. 425, pp. 111900. Date of Electronic Publication: 2026 Jan 02.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Melatonin suppresses glycolysis and coordinately disrupts DNA repair via targeting the YAP1-NAMPT signaling in breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Lai+YW%22">Lai YW</searchLink>; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chu+CY%22">Chu CY</searchLink>; CRISPR Gene Targeting Core Lab, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+ZW%22">Liu ZW</searchLink>; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lu+HY%22">Lu HY</searchLink>; Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Division of Cardiovascular Surgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+CC%22">Lee CC</searchLink>; Department of Food Engineering, Faculty of Engineering and Natural Sciences, Istanbul Sabahattin Zaim University, Istanbul, 343, Türkiye; Department of Food Technology and Nutrition, Faculty of Technologies, Klaipėdos valstybinė kolegija, Higher Education Institution, Lithuania.<br /><searchLink fieldCode="AU" term="%22Lin+MH%22">Lin MH</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan. Electronic address: mhl00001@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Lin+CW%22">Lin CW</searchLink>; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, 807, Taiwan. Electronic address: cwlin@tmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%220227276%22">Chemico-biological interactions</searchLink> [Chem Biol Interact] 2026 Feb 11; Vol. 425, pp. 111900. <i>Date of Electronic Publication: </i>2026 Jan 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>0227276 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7786 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200092797%22">00092797 </searchLink><i>NLM ISO Abbreviation: </i>Chem Biol Interact <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.cbi.2026.111900
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        Text: English
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              Text: 2026 Feb 11
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