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PD-L1 expression combined with immune phenotype is a potential predictor of outcome with PD-1 inhibitor monotherapy in patients with recurrent or metastatic head and neck squamous cell carcinoma.

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Title: PD-L1 expression combined with immune phenotype is a potential predictor of outcome with PD-1 inhibitor monotherapy in patients with recurrent or metastatic head and neck squamous cell carcinoma.
Authors: Kim DH; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Koh J; Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Ahn JS; Lunit Inc, Seoul, Republic of Korea., Moon J; Lunit Inc, Seoul, Republic of Korea., Kang M; Lunit Inc, Seoul, Republic of Korea., Park G; Lunit Inc, Seoul, Republic of Korea., Lim Y; Lunit Inc, Seoul, Republic of Korea., Ock CY; Lunit Inc, Seoul, Republic of Korea., Jeon YK; Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Jung KC; Department of Pathology, Seoul National University Hospital, Seoul, Republic of Korea., Ahn SH; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea., Chung EJ; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea., Kwon SK; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul, Republic of Korea., Keam B; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: bhumsuk@snu.ac.kr.
Source: Oral surgery, oral medicine, oral pathology and oral radiology [Oral Surg Oral Med Oral Pathol Oral Radiol] 2026 May; Vol. 141 (5), pp. 679-689. Date of Electronic Publication: 2025 Dec 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101576782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-4411 (Electronic) NLM ISO Abbreviation: Oral Surg Oral Med Oral Pathol Oral Radiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2212-4411
DOI:10.1016/j.oooo.2025.11.018