Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies.

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Bibliographic Details
Title: Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies.
Authors: Carturan A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Angelos MG; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.; Division of Hematology, University of Colorado Anschutz Medical Campus, Aurora, CO., Guruprasad P; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Patel RP; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Pajarillo R; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Lee A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Espie D; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Zhang Y; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Chiang YH; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology, University of Colorado Anschutz Medical Campus, Aurora, CO.; Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan., Xie W; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Rodriguez JL; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Harris J; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA., Devi P; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA., Afolayan-Oloye OI; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA., Xu J; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Sussman JH; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Elghawy O; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA., Yang A; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Barsouk A; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA., Cho JH; Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ., Shaw CE; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Singh E; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Ugwuanyi O; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Paruzzo L; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Stella F; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Department of Oncology and Hematology, School of Medicine, Università Degli Studi di Milano, Milan, Italy., Liu S; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Nason S; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Imparato A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Rotolo A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Lemoine J; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Barrett DM; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Posey A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Rook AH; Department of Dermatology, University of Pennsylvania, Philadelphia, PA., Pillai V; Division of Hematopathology, Children's Hospital of Philadelphia, Philadelphia, PA., Bagg A; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA., Pileri SA; Division of Hematopathology, Istituto Europeo di Oncologia, Milan, Italy., Liu D; Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ., Tan K; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Schuster SJ; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA., Teachey DT; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Porazzi P; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA., Ruella M; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.
Source: Blood [Blood] 2026 Apr 16; Vol. 147 (16), pp. 1842-1856.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1528-0020
DOI:10.1182/blood.2025031409