View in EDS

Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies.

Saved in:
Bibliographic Details
Title: Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies.
Authors: Carturan A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Angelos MG; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.; Division of Hematology, University of Colorado Anschutz Medical Campus, Aurora, CO., Guruprasad P; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Patel RP; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Pajarillo R; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Lee A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Espie D; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Zhang Y; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Chiang YH; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology, University of Colorado Anschutz Medical Campus, Aurora, CO.; Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan., Xie W; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Rodriguez JL; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Harris J; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA., Devi P; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA., Afolayan-Oloye OI; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA., Xu J; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Sussman JH; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Elghawy O; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA., Yang A; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Barsouk A; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA., Cho JH; Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ., Shaw CE; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Singh E; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Ugwuanyi O; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Paruzzo L; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Stella F; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Department of Oncology and Hematology, School of Medicine, Università Degli Studi di Milano, Milan, Italy., Liu S; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Nason S; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Imparato A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Rotolo A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Lemoine J; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Barrett DM; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Posey A; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA., Rook AH; Department of Dermatology, University of Pennsylvania, Philadelphia, PA., Pillai V; Division of Hematopathology, Children's Hospital of Philadelphia, Philadelphia, PA., Bagg A; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA., Pileri SA; Division of Hematopathology, Istituto Europeo di Oncologia, Milan, Italy., Liu D; Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ., Tan K; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Schuster SJ; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA., Teachey DT; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA., Porazzi P; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA., Ruella M; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.
Source: Blood [Blood] 2026 Apr 16; Vol. 147 (16), pp. 1842-1856.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41490267
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Carturan+A%22">Carturan A</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Angelos+MG%22">Angelos MG</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.; Division of Hematology, University of Colorado Anschutz Medical Campus, Aurora, CO.<br /><searchLink fieldCode="AU" term="%22Guruprasad+P%22">Guruprasad P</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Patel+RP%22">Patel RP</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Pajarillo+R%22">Pajarillo R</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Lee+A%22">Lee A</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Espie+D%22">Espie D</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Chiang+YH%22">Chiang YH</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology, University of Colorado Anschutz Medical Campus, Aurora, CO.; Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Xie+W%22">Xie W</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Rodriguez+JL%22">Rodriguez JL</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Harris+J%22">Harris J</searchLink>; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Devi+P%22">Devi P</searchLink>; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Afolayan-Oloye+OI%22">Afolayan-Oloye OI</searchLink>; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Sussman+JH%22">Sussman JH</searchLink>; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Elghawy+O%22">Elghawy O</searchLink>; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Yang+A%22">Yang A</searchLink>; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Barsouk+A%22">Barsouk A</searchLink>; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Cho+JH%22">Cho JH</searchLink>; Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ.<br /><searchLink fieldCode="AU" term="%22Shaw+CE%22">Shaw CE</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Singh+E%22">Singh E</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Ugwuanyi+O%22">Ugwuanyi O</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Paruzzo+L%22">Paruzzo L</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Stella+F%22">Stella F</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Department of Oncology and Hematology, School of Medicine, Università Degli Studi di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Nason+S%22">Nason S</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Imparato+A%22">Imparato A</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Rotolo+A%22">Rotolo A</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Lemoine+J%22">Lemoine J</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Barrett+DM%22">Barrett DM</searchLink>; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Posey+A%22">Posey A</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Rook+AH%22">Rook AH</searchLink>; Department of Dermatology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Pillai+V%22">Pillai V</searchLink>; Division of Hematopathology, Children's Hospital of Philadelphia, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Bagg+A%22">Bagg A</searchLink>; Division of Hematopathology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Pileri+SA%22">Pileri SA</searchLink>; Division of Hematopathology, Istituto Europeo di Oncologia, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Department of Pathology, Immunology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, NJ.<br /><searchLink fieldCode="AU" term="%22Tan+K%22">Tan K</searchLink>; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Schuster+SJ%22">Schuster SJ</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Teachey+DT%22">Teachey DT</searchLink>; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Porazzi+P%22">Porazzi P</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Ruella+M%22">Ruella M</searchLink>; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA.; Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2026 Apr 16; Vol. 147 (16), pp. 1842-1856.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7603509 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-0020 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200064971%22">00064971 </searchLink><i>NLM ISO Abbreviation: </i>Blood <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41490267
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1182/blood.2025031409
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1842
    Titles:
      – TitleFull: Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Carturan A
      – PersonEntity:
          Name:
            NameFull: Angelos MG
      – PersonEntity:
          Name:
            NameFull: Guruprasad P
      – PersonEntity:
          Name:
            NameFull: Patel RP
      – PersonEntity:
          Name:
            NameFull: Pajarillo R
      – PersonEntity:
          Name:
            NameFull: Lee A
      – PersonEntity:
          Name:
            NameFull: Espie D
      – PersonEntity:
          Name:
            NameFull: Zhang Y
      – PersonEntity:
          Name:
            NameFull: Chiang YH
      – PersonEntity:
          Name:
            NameFull: Xie W
      – PersonEntity:
          Name:
            NameFull: Rodriguez JL
      – PersonEntity:
          Name:
            NameFull: Harris J
      – PersonEntity:
          Name:
            NameFull: Devi P
      – PersonEntity:
          Name:
            NameFull: Afolayan-Oloye OI
      – PersonEntity:
          Name:
            NameFull: Xu J
      – PersonEntity:
          Name:
            NameFull: Sussman JH
      – PersonEntity:
          Name:
            NameFull: Elghawy O
      – PersonEntity:
          Name:
            NameFull: Yang A
      – PersonEntity:
          Name:
            NameFull: Barsouk A
      – PersonEntity:
          Name:
            NameFull: Cho JH
      – PersonEntity:
          Name:
            NameFull: Shaw CE
      – PersonEntity:
          Name:
            NameFull: Singh E
      – PersonEntity:
          Name:
            NameFull: Ugwuanyi O
      – PersonEntity:
          Name:
            NameFull: Paruzzo L
      – PersonEntity:
          Name:
            NameFull: Stella F
      – PersonEntity:
          Name:
            NameFull: Liu S
      – PersonEntity:
          Name:
            NameFull: Nason S
      – PersonEntity:
          Name:
            NameFull: Imparato A
      – PersonEntity:
          Name:
            NameFull: Rotolo A
      – PersonEntity:
          Name:
            NameFull: Lemoine J
      – PersonEntity:
          Name:
            NameFull: Barrett DM
      – PersonEntity:
          Name:
            NameFull: Posey A
      – PersonEntity:
          Name:
            NameFull: Rook AH
      – PersonEntity:
          Name:
            NameFull: Pillai V
      – PersonEntity:
          Name:
            NameFull: Bagg A
      – PersonEntity:
          Name:
            NameFull: Pileri SA
      – PersonEntity:
          Name:
            NameFull: Liu D
      – PersonEntity:
          Name:
            NameFull: Tan K
      – PersonEntity:
          Name:
            NameFull: Schuster SJ
      – PersonEntity:
          Name:
            NameFull: Teachey DT
      – PersonEntity:
          Name:
            NameFull: Porazzi P
      – PersonEntity:
          Name:
            NameFull: Ruella M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 16
              M: 04
              Text: 2026 Apr 16
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1528-0020
          Numbering:
            – Type: volume
              Value: 147
            – Type: issue
              Value: 16
          Titles:
            – TitleFull: Blood
              Type: main
ResultId 1