Multiomics alterations associated with tolerance and response to simulated progressive hemorrhage in healthy adult humans.

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Title: Multiomics alterations associated with tolerance and response to simulated progressive hemorrhage in healthy adult humans.
Authors: Misganaw B; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States.; Culmen International, LLC, Alexandria, Virginia, United States., Muhie S; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States.; The Geneva Foundation, Tacoma, Washington, United States., Gautam A; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States., Miller SA; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States., Crespo Rosales IN; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States.; Culmen International, LLC, Alexandria, Virginia, United States., Dimitrov GI; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States.; Culmen International, LLC, Alexandria, Virginia, United States., Sowe B; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States., Johnson CP; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States., Roberts SK; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States., Regimbal RJ; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States., Wiggins CC; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States.; Department of Kinesiology, Michigan State University, East Lansing, Michigan, United States., Joyner MJ; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States., Curry TB; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States., Convertino VA; US Army Institute of Surgical Research, JBSA Fort Sam Houston, San Antonio, Texas, United States., Hammamieh R; Medical Readiness Systems Biology, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States.
Source: Physiological genomics [Physiol Genomics] 2026 Feb 01; Vol. 58 (2), pp. 102-114. Date of Electronic Publication: 2026 Jan 06.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 9815683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-2267 (Electronic) Linking ISSN: 10948341 NLM ISO Abbreviation: Physiol Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1531-2267
DOI:10.1152/physiolgenomics.00253.2025