Sigma-1 receptor positive allosteric modulator promotes neuronal survival and improves cognitive deficits in AD mice via sigma-1 receptor/ERK pathway.
Saved in:
| Title: | Sigma-1 receptor positive allosteric modulator promotes neuronal survival and improves cognitive deficits in AD mice via sigma-1 receptor/ERK pathway. |
|---|---|
| Authors: | Wang XY; Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, 999078, China.; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China., Zhou WS; Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, 999078, China., Gaur U; Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, 999078, China., Zhen XC; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China. zhenxuechu@suda.edu.cn., Zheng WH; Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macau, 999078, China. wenhuazheng@um.edu.mo. |
| Source: | Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 Apr; Vol. 47 (4), pp. 888-902. Date of Electronic Publication: 2026 Jan 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1745-7254 |
|---|---|
| DOI: | 10.1038/s41401-025-01703-7 |
