NUP98 rearrangements in adult AML patients: evaluation of clinical implications and identification of novel fusion partners.

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Title: NUP98 rearrangements in adult AML patients: evaluation of clinical implications and identification of novel fusion partners.
Authors: Chonabayashi K; Department of Hematology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan., Iwasaki M; Department of Hematology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Kanda J; Department of Hematology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Takamori H; Division of Hematopoietic Disease Control, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Yoda A; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan., Kawata T; Department of Hematology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Hematology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Mizuta S; Department of Clinical Laboratory, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Sakurada M; Department of Hematology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Kondo T; Department of Hematology, Kobe City Medical Center General Hospital, Hyogo, Japan., Hiramoto N; Department of Hematology, Kobe City Medical Center General Hospital, Hyogo, Japan., Ueda Y; Department of Hematology/Oncology, Kurashiki Central Hospital, Kurashiki, Japan., Gotoh A; Department of Hematology, Tokyo Medical University, Tokyo, Japan., Watanabe M; Department of Hematology, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan., Kasahara S; Department of Hematology, Gifu Municipal Hospital, Gifu, Japan.; Laboratory of Pharmaceutical Health Care and Promotion, Gifu Pharmaceutical University, Gifu, Japan., Ishikawa Y; Japan Adult Leukemia Study Group (JALSG), Osaka, Japan., Kiyoi H; Japan Adult Leukemia Study Group (JALSG), Osaka, Japan., Imada K; Department of Hematology, Japanese Red Cross Osaka Hospital, Osaka, Japan., Mitani K; Department of Hematology and Oncology, Dokkyo Medical University, Tochigi, Japan., Kitano T; Department of Hematology, Medical Research Institute Kitano Hospital, Osaka, Japan., Arima N; Department of Hematology, Shinko Hospital, Hyogo, Japan., Nakabo Y; The Center for Hematological Diseases, Takeda General Hospital, Kyoto, Japan., Sezaki N; Department of Hematology, Chugoku Central Hospital, Hiroshima, Japan., Kanemura N; Department of Hematology and Infectious Disease, Gifu University Hospital, Gifu, Japan., Fukuda T; Department of Hematology, National Cancer Center Hospital, Tokyo, Japan., Ichikawa M; Department of Hematology, NTT Medical Center, Tokyo, Tokyo, Japan., Miyazaki Y; Department of Hematology, Atomic Bomb Disease and Hibakusya Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan., Fuji S; Department of Hematology, Osaka International Cancer Institute, Osaka, Japan., Sakata-Yanagimoto M; Department of Hematology, Institute of Medicine, University of Tsukuba, Ibaraki, Japan.; Department of Hematology, University of Tsukuba Hospital, Division of Advanced Hemato-Oncology, Tsukuba, Japan.; Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan., Yoshida Y; Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan., Takaori-Kondo A; Department of Hematology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Ogawa S; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan., Nannya Y; Division of Hematopoietic Disease Control, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. ynanya@ims.u-tokyo.ac.jp.; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan. ynanya@ims.u-tokyo.ac.jp.
Source: Leukemia [Leukemia] 2026 Mar; Vol. 40 (3), pp. 491-501. Date of Electronic Publication: 2026 Jan 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5551
DOI:10.1038/s41375-025-02848-4