Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss.

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Title: Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss.
Authors: Ali S; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Berg AH; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Yamashita M; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Covarrubias AE; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Mundell J; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Shah PN; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Zhang R; Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Dupont V; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Shin BH; Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Yang S; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Katiki M; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Murali R; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Pisarska MD; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Thadhani R; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA., Heeger PS; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Jordan SC; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Stan.Jordan@cshs.org.; Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Stan.Jordan@cshs.org., Karumanchi SA; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA. sananth.karumanchi@csmc.edu.
Source: Nature communications [Nat Commun] 2026 Jan 08; Vol. 17 (1), pp. 1325. Date of Electronic Publication: 2026 Jan 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-025-68077-6