Voxelwise correlation of neighbors as a hypothesis driven framework for characterizing white matter lesion heterogeneity.

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Bibliographic Details
Title: Voxelwise correlation of neighbors as a hypothesis driven framework for characterizing white matter lesion heterogeneity.
Authors: Alshikho MJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA.; Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Lao PJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA.; Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Edwards NC; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA.; Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Pyne JD; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA.; Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Cotton-Samuel D; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA., Morales CD; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA., Berroa J; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA., Morel N; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA., Benavides A; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA., Ventura RE; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA., Lippert RV; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA., Hale C; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA., Manly JJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA.; Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Mayeux RP; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA.; Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Brickman AM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, P&S Box 16, New York, NY, 10032, USA. amb2139@columbia.edu.; Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. amb2139@columbia.edu.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. amb2139@columbia.edu.
Source: Scientific reports [Sci Rep] 2026 Jan 08; Vol. 16 (1), pp. 3427. Date of Electronic Publication: 2026 Jan 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-025-33418-4