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A vascularized three-dimensional model integrating primary breast tumor cells and microvascular fragments: mimicking the tumor microenvironment involved in chemoresistance.

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Bibliographic Details
Title: A vascularized three-dimensional model integrating primary breast tumor cells and microvascular fragments: mimicking the tumor microenvironment involved in chemoresistance.
Authors: Lo Cicero A; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16-90128, Palermo, Italy. alessandra.locicero@unipa.it., La Monica F; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16-90128, Palermo, Italy., Lo Buglio G; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16-90128, Palermo, Italy.; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark., Campora S; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16-90128, Palermo, Italy., Gangemi F; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16-90128, Palermo, Italy., Cinà P; Abiel srl, Palermo, Italy., Salamone M; Institute for Biomedical Research and Innovation, National Research Council (IRIB-CNR), Palermo, Italy., Lo Pinto M; Proteomics Group of Ri.MED Foundation, Research Department IRCCS ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione), Palermo, Italy., Scilabra SD; Proteomics Group of Ri.MED Foundation, Research Department IRCCS ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione), Palermo, Italy., Ghersi G; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Viale delle Scienze, Ed. 16-90128, Palermo, Italy. giulio.ghersi@unipa.it.; Abiel srl, Palermo, Italy. giulio.ghersi@unipa.it.
Source: Cancer cell international [Cancer Cell Int] 2026 Jan 08; Vol. 26 (1), pp. 74. Date of Electronic Publication: 2026 Jan 08.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139795 Publication Model: Electronic Cited Medium: Print ISSN: 1475-2867 (Print) Linking ISSN: 14752867 NLM ISO Abbreviation: Cancer Cell Int Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1475-2867
DOI:10.1186/s12935-025-04154-6