Haplotype-Resolved Genomics Reveals Conserved Chromatin Architecture and Epigenetic Constraints of Human Neocentromeres.

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Bibliographic Details
Title: Haplotype-Resolved Genomics Reveals Conserved Chromatin Architecture and Epigenetic Constraints of Human Neocentromeres.
Authors: Hoyt SJ; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA.; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA., Hartley GA; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA.; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA., Antopia MC; Department of Genetics, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Tullius TW; Lewis-Sigler Institute, Princeton University, Princeton, NJ, USA., Taylor DJ; Department of Biology, Johns Hopkins University, Baltimore, MD, USA., Tillquist NM; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA., Neph S; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA., Pauloski N; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA., Munson KM; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA., Hoekzema K; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA., Eichler EE; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA., Stergachis AB; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA., Logsdon GA; Department of Genetics, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA., O'Neill RJ; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA.; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 25. Date of Electronic Publication: 2025 Dec 25.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2025.12.23.696241