HDAC3 Mediates Hippocampal Microglial Pyroptosis Via the STING/NLRP3 Pathway and Contributes To Cognitive Impairment in Sepsis-Associated Encephalopathy.
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| Title: | HDAC3 Mediates Hippocampal Microglial Pyroptosis Via the STING/NLRP3 Pathway and Contributes To Cognitive Impairment in Sepsis-Associated Encephalopathy. |
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| Authors: | Cai M; Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China., Shao H; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China., Xu S; Department of Anesthesiology, Jinling Clinical Medical College, Nanjing Medical University, Nanjing, 210002, China., Wang H; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China., Yang MJ; Department of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, China., Zhu T; Department of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, China., Chen J; Minister of Education Key Laboratory Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China., Li GZ; Minister of Education Key Laboratory Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China., Lu SF; Minister of Education Key Laboratory Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China., Zang YY; Minister of Education Key Laboratory Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China., Ji MH; Department of Anesthesiology, The Second Affiliated Hospital, Nanjing Medical University, Nanjing, 210011, China. jimuhuo2009@sina.com., Shen JC; Department of Anesthesiology, Jinling Clinical Medical College, Nanjing Medical University, Nanjing, 210002, China. yyshen0203@163.com.; Department of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, China. yyshen0203@163.com., Jia M; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. jiamin0320@126.com., Yang JJ; Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. yjyangjj@126.com.; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. yjyangjj@126.com. |
| Source: | Inflammation [Inflammation] 2026 Jan 10; Vol. 49 (1), pp. 39. Date of Electronic Publication: 2026 Jan 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7600105 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2576 (Electronic) Linking ISSN: 03603997 NLM ISO Abbreviation: Inflammation Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1573-2576 |
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| DOI: | 10.1007/s10753-025-02360-y |
