The Impact of RNA Polymerase III-Related Leukodystrophy on Nonaffected Family Members: A Qualitative Study.

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Title: The Impact of RNA Polymerase III-Related Leukodystrophy on Nonaffected Family Members: A Qualitative Study.
Authors: Le A; Child Health and Human Development Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada; Department of Neurology and Neurosurgery, McGill University, Montréal, Québec, Canada., Thibault KA; Child Health and Human Development Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada; Department of Neurology and Neurosurgery, McGill University, Montréal, Québec, Canada; Faculté de Médecine, Université de Montréal, Montréal, Québec, Canada., Yazdani PA; Child Health and Human Development Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada; Department of Neurology and Neurosurgery, McGill University, Montréal, Québec, Canada; Faculté de Médecine, Université de Montréal, Montréal, Québec, Canada., Chapleau A; Child Health and Human Development Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada; Department of Neurology and Neurosurgery, McGill University, Montréal, Québec, Canada., van Voorst RJ; Department of Pediatric Neurology, Emma Children's Hospital, Amsterdam University Medical Centre, Amsterdam, The Netherlands; Amsterdam Leukodystrophy Center, Amsterdam Neuroscience, Cellular & Molecular Mechanisms, Amsterdam, The Netherlands., Bertini E; Unit of Muscular and Neurodegenerative Diseases, Bambino Gesù Children's Hospital, IRCCS, Rome, Lazio, Italy., Nicita F; Unit of Muscular and Neurodegenerative Diseases, Bambino Gesù Children's Hospital, IRCCS, Rome, Lazio, Italy., Pohl D; Division of Pediatric Neurology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada., Venkateswaran S; Division of Neurology, Department of Pediatrics, Children's Hospital, London Health Sciences Center, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Keller S; Division of Pediatric Neurology, Department of Pediatrics, Children's Healthcare of Atlanta and Emory University, Atlanta, Georgia., Renaud D; Departments of Neurology and Pediatrics, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Gonzalez Moron D; Neurogenetics Unit, Department of Neurology, Hospital JM Ramos Mejia and CONICET-Universidad Austral, Buenos Aires, Argentina., Kauffman M; Neurogenetics Unit, Department of Neurology, Hospital JM Ramos Mejia and CONICET-Universidad Austral, Buenos Aires, Argentina., De Assis Pereira D; Division of Pediatric Neurology, Department of Human Reproduction and Childhood, Pontifical Catholic University of São Paulo (PUC-SP), São Paulo, Brazil; Division of Pediatric Neurology, Department of Human Reproduction and Childhood, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Vanderver A; Division of Neurology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., van der Knaap MS; Department of Pediatric Neurology, Emma Children's Hospital, Amsterdam University Medical Centre, Amsterdam, The Netherlands; Amsterdam Leukodystrophy Center, Amsterdam Neuroscience, Cellular & Molecular Mechanisms, Amsterdam, The Netherlands; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Morsa M; Adaptation, Resilience, and Change Research Unit, Department of Psychology, Université de Liège, Belgium., Bernard G; Child Health and Human Development Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada; Department of Neurology and Neurosurgery, McGill University, Montréal, Québec, Canada; Department of Pediatrics, McGill University, Montréal, Québec, Canada; Department of Human Genetics, McGill University, Montréal, Québec, Canada; Division of Medical Genetics, Department of Specialized Medicine, McGill University Health Centre, Montréal, Québec, Canada. Electronic address: genevieve.bernard@mcgill.ca.
Source: Pediatric neurology [Pediatr Neurol] 2026 Mar; Vol. 176, pp. 31-40. Date of Electronic Publication: 2025 Dec 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Publishing Country of Publication: United States NLM ID: 8508183 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5150 (Electronic) Linking ISSN: 08878994 NLM ISO Abbreviation: Pediatr Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-5150
DOI:10.1016/j.pediatrneurol.2025.12.004