Single-cell transcriptomics showed that maternal polychlorinated biphenyl exposure dysregulated cell type-specific metabolic responses in the livers of female mouse offsprings.

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Title: Single-cell transcriptomics showed that maternal polychlorinated biphenyl exposure dysregulated cell type-specific metabolic responses in the livers of female mouse offsprings.
Authors: Lim JJ; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), University of Washington, Seattle, Washington; Institute for Systems Biology, Seattle, Washington., Suh Y; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), University of Washington, Seattle, Washington; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon., Li X; Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa., Wilson RJ; Department of Molecular Biosciences, University of California, Davis, California., Lehmler HJ; Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa., Lein PJ; Department of Molecular Biosciences, University of California, Davis, California., Cui JY; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), University of Washington, Seattle, Washington; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon. Electronic address: juliayuecui2011@gmail.com.
Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2026 Feb; Vol. 54 (2), pp. 100174. Date of Electronic Publication: 2025 Sep 25.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1521-009X
DOI:10.1016/j.dmd.2025.100174