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Single-cell transcriptomics showed that maternal polychlorinated biphenyl exposure dysregulated cell type-specific metabolic responses in the livers of female mouse offsprings.

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Title: Single-cell transcriptomics showed that maternal polychlorinated biphenyl exposure dysregulated cell type-specific metabolic responses in the livers of female mouse offsprings.
Authors: Lim JJ; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), University of Washington, Seattle, Washington; Institute for Systems Biology, Seattle, Washington., Suh Y; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), University of Washington, Seattle, Washington; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon., Li X; Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa., Wilson RJ; Department of Molecular Biosciences, University of California, Davis, California., Lehmler HJ; Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa., Lein PJ; Department of Molecular Biosciences, University of California, Davis, California., Cui JY; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), University of Washington, Seattle, Washington; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon. Electronic address: juliayuecui2011@gmail.com.
Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2026 Feb; Vol. 54 (2), pp. 100174. Date of Electronic Publication: 2025 Sep 25.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell transcriptomics showed that maternal polychlorinated biphenyl exposure dysregulated cell type-specific metabolic responses in the livers of female mouse offsprings.
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  Data: <searchLink fieldCode="AU" term="%22Lim+JJ%22">Lim JJ</searchLink>; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), University of Washington, Seattle, Washington; Institute for Systems Biology, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Suh+Y%22">Suh Y</searchLink>; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), University of Washington, Seattle, Washington; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa.<br /><searchLink fieldCode="AU" term="%22Wilson+RJ%22">Wilson RJ</searchLink>; Department of Molecular Biosciences, University of California, Davis, California.<br /><searchLink fieldCode="AU" term="%22Lehmler+HJ%22">Lehmler HJ</searchLink>; Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa.<br /><searchLink fieldCode="AU" term="%22Lein+PJ%22">Lein PJ</searchLink>; Department of Molecular Biosciences, University of California, Davis, California.<br /><searchLink fieldCode="AU" term="%22Cui+JY%22">Cui JY</searchLink>; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington; Environmental Health and Microbiome Research Center (EHMBRACE), University of Washington, Seattle, Washington; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon. Electronic address: juliayuecui2011@gmail.com.
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        Value: 10.1016/j.dmd.2025.100174
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      – TitleFull: Single-cell transcriptomics showed that maternal polychlorinated biphenyl exposure dysregulated cell type-specific metabolic responses in the livers of female mouse offsprings.
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              Text: 2026 Feb
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