Integrative analysis across metagenomic taxonomic classifiers: A case study of the gut microbiome in aging and longevity in the Integrative Longevity Omics Study.

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Title: Integrative analysis across metagenomic taxonomic classifiers: A case study of the gut microbiome in aging and longevity in the Integrative Longevity Omics Study.
Authors: Karagiannis TT; Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts, United States of America.; Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, United States of America., Chen Y; Clinical Translational and Science Institute, Tufts Medical Center, Boston, Massachusetts, United States of America., Bald S; Bioinformatics Program, Faculty of Computing and Data Science, Boston University, Boston, Massachusetts, United States of America., Tai A; Department of Immunology, Tufts University School of Medicine, Boston, Massachusetts, United States of America.; Data Intensive Studies Center, Tufts University, Medford, Massachusetts, United States of America., Reed ER; Department of Medicine, Albert Einstein College of Medicine, New York, New York, United States of America., Milman S; Department of Medicine, Albert Einstein College of Medicine, New York, New York, United States of America., Andersen SL; Department of Medicine, Geriatrics Section, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America., Perls TT; Department of Medicine, Geriatrics Section, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America., Segrè D; Bioinformatics Program, Faculty of Computing and Data Science, Boston University, Boston, Massachusetts, United States of America.; Department of Biology, Boston University, Boston, Massachusetts, United States of America., Sebastiani P; Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts, United States of America.; Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, United States of America.; Bioinformatics Program, Faculty of Computing and Data Science, Boston University, Boston, Massachusetts, United States of America.; Data Intensive Studies Center, Tufts University, Medford, Massachusetts, United States of America., Short MI; Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts, United States of America.; Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, United States of America.
Source: PLoS computational biology [PLoS Comput Biol] 2026 Jan 12; Vol. 22 (1), pp. e1013883. Date of Electronic Publication: 2026 Jan 12 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1553-7358
DOI:10.1371/journal.pcbi.1013883