Distribution of capsule and O types in Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: A meta-analysis of genome-predicted serotype prevalence to inform potential vaccine coverage.
Saved in:
| Title: | Distribution of capsule and O types in Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: A meta-analysis of genome-predicted serotype prevalence to inform potential vaccine coverage. |
|---|---|
| Authors: | Stanton TD; Department of Infectious Diseases, School of Translational Medicine, Monash University, Melbourne, Australia.; Centre to Impact AMR, Monash University, Clayton, Victoria, Australia., Keegan SP; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom., Abdulahi JA; Department of Infectious Disease Epidemiology and International Health, London School of Hygiene and Tropical Medicine, London, United Kingdom., Amulele AV; Bioscience Department, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Bates M; School of Natural Sciences, University of Lincoln, Lincoln, United Kingdom., Heinz E; Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.; Parasites and Microbes Program, Wellcome Sanger Institute, Hinxton, United Kingdom., Hooda Y; Child Health Research Foundation, Dhaka, Bangladesh., Hu W; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, United States of America., Jain K; Pediatrics, All India Institute of Medical Sciences, New Delhi, India., Kanwar S; Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Magobo R; Centre for Healthcare Associated Infections, Antimicrobial Resistance and Mycoses, National Institute for Communicable Diseases, Johannesburg, South Africa.; Division of Public Health, Societies and Belonging, Human Sciences Research Council, Pretoria, South Africa., Olwagen CP; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa., Tembo JM; Department of Infectious Diseases, HerpeZ, Lusaka, Zambia., Sonda T; Bioinformatics Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania., Strysko J; Botswana-University of Pennsylvania Partnership, University of Pennsylvania, Gaborone, Botswana.; Division of General Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Tigoi CC; Bioscience Department, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Amin SA; CITRIC Center for Bioinformatics and Computational Biology, Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Bittinger K; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, United States of America.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Center for Microbial Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Cornick J; Clinical Infection, Microbiology and Immunology, University of Liverpool, Liverpool, United Kingdom.; Malawi Liverpool Wellcome Programme, Kamuzu University of Health Sciences, Blantyre, Malawi., Foster-Nyarko E; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom., Gumbi W; Bioscience Department, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Hotwani A; Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Iqbal N; Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan.; Department of Biotechnology and Informatics, Faculty of Life Sciences & Informatics, BUITEMS, Quetta, Pakistan., Jones SM; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, United States of America., Kabir F; Infectious Diseases Research laboratory, Department of Paediatrics & Child Health, Aga Khan University, Karachi, Pakistan., Khan W; CITRIC Center for Bioinformatics and Computational Biology, Department of Pediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Musyani CL; Antimicrobial Resistance Unit, Zambia National Public Health Institute, Lusaka, Zambia.; Institute of Basic and Biomedical Sciences, Levy Mwanawasa Medical University, Lusaka, Zambia., McGann CM; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Mittal V; Pediatrics, All India Institute of Medical Sciences, New Delhi, India., Moustafa AM; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, United States of America.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Center for Microbial Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Musicha P; Malawi Liverpool Wellcome Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Mwansa JCL; Directorate of Research and Post Graduate Studies, Lusaka Apex Medical University, Lusaka, Zambia., Ndumba ML; Bioscience Department, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Odih EE; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom., Omuoyo DO; Bioscience Department, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Pearse O; Malawi Liverpool Wellcome Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Phillips LT; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom., Planet PJ; Center for Microbial Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.; Pediatrics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Rasool AA; Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Rodrigues CMC; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Department of Paediatrics, Imperial College Healthcare NHS Trust, London, United Kingdom.; Pathogen Genomics Programme, UK Health Security Agency, London, United Kingdom., Sands K; Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom.; Department of Medical Microbiology, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom., Tanmoy AM; Child Health Research Foundation, Dhaka, Bangladesh., Theiller E; Center for Microbial Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Zuza AM; Malawi Liverpool Wellcome Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.; The School of Medicine, University of St Andrews, St Andrews, United Kingdom., Basu S; Division of Bacteriology, ICMR-National Institute for Research in Bacterial Infections (formerly ICMR-NICED), Kolkata, India., Chan GJ; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.; Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Iregbu KC; Department of Medical Microbiology, College of Health Sciences, University of Abuja, Abuja, Nigeria.; Department of Medical Microbiology, National Hospital Abuja, Abuja, Nigeria., Mazarati JB; Health Sciences, INES-RUHENGERI, Musanze, Rwanda.; INES Centre for Genomic Biology, Musanze, Rwanda., Alemayehu SS; Department of Microbiology, Immunology and Parasitology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia., Walsh TR; Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford, United Kingdom.; International Centre for Antimicrobial Resistance Solutions, Copenhagen, Denmark., Zahra R; Department of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan.; Department of Clinical Microbiology, School of Medicine, Trinity College Dublin, St James's Hospital, Dublin, Ireland., Dramowski A; Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Fwoloshi S; School of Medicine, University Teaching Hospital, University of Zambia, Lusaka, Zambia.; Infectious Diseases Unit, Department of Internal Medicine, UTH, Lusaka, Zambia., Labi AK; Department of Medical Microbiology, University of Ghana Medical School, Accra, Ghana., Madrid L; Department of Infectious Disease Epidemiology and International Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.; College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia., Obeng-Nkrumah N; Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, College of Health Sciences, University of Ghana, Accra, Ghana., Ojok D; Central Laboratory, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia., Wadugu BD; Biotechnology Laboratory, Kilimanjaro Clinical Research Institute, Moshi, Tanzania., Whitelaw AC; Division of Medical Microbiology and Immunology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.; National Health Laboratory Service, Tygerberg Hospital, Cape Town, South Africa., Bethou A; Department of Neonatology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India., Bhargava A; Department of Microbiology, All India Institute of Medical Sciences, Raipur, India., Jindal A; Pediatrics, All India Institute of Medical Sciences, Raipur, India., Nanavati RN; Department of Neonatology, Seth GS Medical College and KEM Hospital, Mumbai, India., Prasad PS; Department of Microbiology, Seth GS Medical College & KEM Hospital, Mumbai, India., Sastry A; Microbiology, JIPMER, Puducherry, India., Farooqi JQ; Department of Pathology and Laboratory Medicine, The Aga Khan University, Karachi, Pakistan., Ghanchi N; Department of Pathology and Laboratory Medicine, The Aga Khan University, Karachi, Pakistan., Jehan F; Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Khan E; Department of Pathology and Laboratory Medicine, The Aga Khan University, Karachi, Pakistan., Agarwal RK; Pediatrics, All India Institute of Medical Sciences, New Delhi, India., Aiken AM; Department of Infectious Disease Epidemiology and International Health, London School of Hygiene and Tropical Medicine, London, United Kingdom., Berkley JA; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Clinical Research Department, KEMRI/Wellcome Trust Research Programme, Kilifi, Kenya., Coffin SE; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America., Feasey NA; Malawi Liverpool Wellcome Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.; The School of Medicine, University of St Andrews, St Andrews, United Kingdom., Govender NP; Wits Mycology Division, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; Division of the National Health Laboratory Service, National Institute for Communicable Diseases, Johannesburg, South Africa.; Wits Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Hamer DH; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, United States of America.; Section of Infectious Diseases, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, United States of America., Madhi SA; South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa.; Wits Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Nisar MI; Department of Paediatrics and Child Health, The Aga Khan University, Karachi, Pakistan., Saha SK; Child Health Research Foundation, Dhaka, Bangladesh., Saha S; Child Health Research Foundation, Dhaka, Bangladesh., Sankar MJ; Pediatrics, All India Institute of Medical Sciences, New Delhi, India., Wyres KL; Department of Infectious Diseases, School of Translational Medicine, Monash University, Melbourne, Australia.; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom., Holt KE; Department of Infectious Diseases, School of Translational Medicine, Monash University, Melbourne, Australia.; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom. |
| Source: | PLoS medicine [PLoS Med] 2026 Jan 12; Vol. 23 (1), pp. e1004879. Date of Electronic Publication: 2026 Jan 12 (Print Publication: 2026). |
| Publication Type: | Journal Article; Meta-Analysis |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101231360 Publication Model: eCollection Cited Medium: Internet ISSN: 1549-1676 (Electronic) Linking ISSN: 15491277 NLM ISO Abbreviation: PLoS Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1549-1676 |
|---|---|
| DOI: | 10.1371/journal.pmed.1004879 |
