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Discovery of disrupted sustained attention and altered functional connectivity in far-from-onset Huntington's disease gene-expanded young adults.

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Title: Discovery of disrupted sustained attention and altered functional connectivity in far-from-onset Huntington's disease gene-expanded young adults.
Authors: Langley C; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK., Leocadi M; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Hobbs NZ; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Farag M; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Murphy MJ; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Fayer K; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Scahill RI; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Rowe JB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK., Robbins TW; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.; Department of Psychology, University of Cambridge, Cambridge, UK., Tabrizi SJ; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Sahakian BJ; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Jan; Vol. 22 (1), pp. e70944.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Discovery of disrupted sustained attention and altered functional connectivity in far-from-onset Huntington's disease gene-expanded young adults.
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  Data: <searchLink fieldCode="AU" term="%22Langley+C%22">Langley C</searchLink>; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Leocadi+M%22">Leocadi M</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hobbs+NZ%22">Hobbs NZ</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Farag+M%22">Farag M</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Murphy+MJ%22">Murphy MJ</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Fayer+K%22">Fayer K</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Scahill+RI%22">Scahill RI</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Rowe+JB%22">Rowe JB</searchLink>; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Robbins+TW%22">Robbins TW</searchLink>; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.; Department of Psychology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Tabrizi+SJ%22">Tabrizi SJ</searchLink>; Huntington's Disease Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Sahakian+BJ%22">Sahakian BJ</searchLink>; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.
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  Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2026 Jan; Vol. 22 (1), pp. e70944.
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              Text: 2026 Jan
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