Proteomic analysis of endothelial progenitor cells secretome identifies Serpine 1 as a potent regulator of osteogenesis.

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Title: Proteomic analysis of endothelial progenitor cells secretome identifies Serpine 1 as a potent regulator of osteogenesis.
Authors: Asbi T; Department of Periodontology, Rambam Health Care Campus, Haifa, Israel.; Laboratory for Bone Repair, CRIR Institute, Rambam Health Care Campus, Haifa, Israel., Tamari T; Laboratory for Bone Repair, CRIR Institute, Rambam Health Care Campus, Haifa, Israel., Doppelt-Flikshtain O; Laboratory for Bone Repair, CRIR Institute, Rambam Health Care Campus, Haifa, Israel., Regev-Yehishalom O; Department of Chemical Engineering, Technion-Israel Institute of Technology, Haifa, Israel., Zusmanovich I; Department of Chemical Engineering, Technion-Israel Institute of Technology, Haifa, Israel., Younis A; Department of Periodontology, Rambam Health Care Campus, Haifa, Israel.; Laboratory for Bone Repair, CRIR Institute, Rambam Health Care Campus, Haifa, Israel., Oguen-Alon T; Department of Prosthodontics, Rambam Health Care Campus, Haifa, Israel., Berg T; Laboratory for Bone Repair, CRIR Institute, Rambam Health Care Campus, Haifa, Israel., Bianco-Peled H; Department of Chemical Engineering, Technion-Israel Institute of Technology, Haifa, Israel., Zigdon-Giladi H; Department of Periodontology, Rambam Health Care Campus, Haifa, Israel. h_zigdon@rambam.health.gov.il.; Laboratory for Bone Repair, CRIR Institute, Rambam Health Care Campus, Haifa, Israel. h_zigdon@rambam.health.gov.il.; Rappaport Faculty of Medicine, Technion - Israeli Institute of Technology, Haifa, Israel. h_zigdon@rambam.health.gov.il.
Source: Scientific reports [Sci Rep] 2026 Jan 13; Vol. 16 (1), pp. 5165. Date of Electronic Publication: 2026 Jan 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-026-36048-6