View in EDS HTML Full Text PDF Full Text

Sarcomeric remodelling in human heart failure unraveled by single molecule long read sequencing.

Saved in:
Bibliographic Details
Title: Sarcomeric remodelling in human heart failure unraveled by single molecule long read sequencing.
Authors: Haas J; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany., Schudy S; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany., Rauscher B; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Muñoz Verdú A; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany., Roßkopf S; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany., Reich C; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany., Donmez Yalcin G; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany., Yalcin A; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany., Seeger T; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany., Dieterich C; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany., Taft MH; Institute for Biophysical Chemistry, Hannover Medical School, Fritz-Hartmann-Centre for Medical Research, 30625, Hannover, Germany., Freichel M; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Pharmacology, University of Heidelberg, Heidelberg, Germany., Grimm D; German Center for Infection Research (DZIF) and German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Infectious Diseases/Virology, Section Viral Vector Technologies, Medical Faculty, BioQuant, Heidelberg University, Heidelberg, Germany., Manstein D; Division for Structural Biochemistry, Hannover Medical School, 30625, Hannover, Germany., Backs J; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany., Frey N; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany., Steinmetz L; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Genome Technology Center, Palo Alto, CA, USA., Meder B; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany. Benjamin.meder@med.uni-heidelberg.de.; Informatics for Life, Heidelberg, Germany. Benjamin.meder@med.uni-heidelberg.de.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany. Benjamin.meder@med.uni-heidelberg.de.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Feb; Vol. 18 (2), pp. 824-845. Date of Electronic Publication: 2026 Jan 13.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41530494
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Sarcomeric remodelling in human heart failure unraveled by single molecule long read sequencing.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Haas+J%22">Haas J</searchLink>; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schudy+S%22">Schudy S</searchLink>; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Rauscher+B%22">Rauscher B</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Muñoz+Verdú+A%22">Muñoz Verdú A</searchLink>; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Roßkopf+S%22">Roßkopf S</searchLink>; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reich+C%22">Reich C</searchLink>; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Donmez+Yalcin+G%22">Donmez Yalcin G</searchLink>; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Yalcin+A%22">Yalcin A</searchLink>; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.; Informatics for Life, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Seeger+T%22">Seeger T</searchLink>; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Dieterich+C%22">Dieterich C</searchLink>; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Taft+MH%22">Taft MH</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Fritz-Hartmann-Centre for Medical Research, 30625, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Freichel+M%22">Freichel M</searchLink>; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Pharmacology, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Grimm+D%22">Grimm D</searchLink>; German Center for Infection Research (DZIF) and German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Infectious Diseases/Virology, Section Viral Vector Technologies, Medical Faculty, BioQuant, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Manstein+D%22">Manstein D</searchLink>; Division for Structural Biochemistry, Hannover Medical School, 30625, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Backs+J%22">Backs J</searchLink>; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Frey+N%22">Frey N</searchLink>; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany.; Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Steinmetz+L%22">Steinmetz L</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Genome Technology Center, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Meder+B%22">Meder B</searchLink>; Precision Digital Health Unit of the Department of Internal Medicine III, Heidelberg University, Heidelberg, Germany. Benjamin.meder@med.uni-heidelberg.de.; Informatics for Life, Heidelberg, Germany. Benjamin.meder@med.uni-heidelberg.de.; German Center for Cardiovascular Research (DZHK), partner site Heidelberg, Heidelberg, Germany. Benjamin.meder@med.uni-heidelberg.de.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2026 Feb; Vol. 18 (2), pp. 824-845. <i>Date of Electronic Publication: </i>2026 Jan 13.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41530494
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s44321-025-00370-9
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 824
    Titles:
      – TitleFull: Sarcomeric remodelling in human heart failure unraveled by single molecule long read sequencing.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Haas J
      – PersonEntity:
          Name:
            NameFull: Schudy S
      – PersonEntity:
          Name:
            NameFull: Rauscher B
      – PersonEntity:
          Name:
            NameFull: Muñoz Verdú A
      – PersonEntity:
          Name:
            NameFull: Roßkopf S
      – PersonEntity:
          Name:
            NameFull: Reich C
      – PersonEntity:
          Name:
            NameFull: Donmez Yalcin G
      – PersonEntity:
          Name:
            NameFull: Yalcin A
      – PersonEntity:
          Name:
            NameFull: Seeger T
      – PersonEntity:
          Name:
            NameFull: Dieterich C
      – PersonEntity:
          Name:
            NameFull: Taft MH
      – PersonEntity:
          Name:
            NameFull: Freichel M
      – PersonEntity:
          Name:
            NameFull: Grimm D
      – PersonEntity:
          Name:
            NameFull: Manstein D
      – PersonEntity:
          Name:
            NameFull: Backs J
      – PersonEntity:
          Name:
            NameFull: Frey N
      – PersonEntity:
          Name:
            NameFull: Steinmetz L
      – PersonEntity:
          Name:
            NameFull: Meder B
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2026 Feb
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1757-4684
          Numbering:
            – Type: volume
              Value: 18
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: EMBO molecular medicine
              Type: main
ResultId 1