SIRT3 attenuates AGEs-induced senescence in human granulosa cells through enhancing mitophagy.

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Title: SIRT3 attenuates AGEs-induced senescence in human granulosa cells through enhancing mitophagy.
Authors: Li S; Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei, 230031, China., Tang M; NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, China.; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China, Anhui Medical University, Hefei, 230032, China.; Anhui Province Key Laboratory of Reproductive Disorders and Obstetrics and Gynecology Diseases, Hefei, 230032, China., Zhu S; Anhui Province Key Laboratory of Reproductive Disorders and Obstetrics and Gynecology Diseases, Hefei, 230032, China.; Biopreservation and Artificial Organs, Anhui Provincial Engineering Research Center, Anhui Medical University, Hefei, 230032, China., Zhang Z; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230088, China. zzg_100@163.com.; NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, China. zzg_100@163.com.; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China, Anhui Medical University, Hefei, 230032, China. zzg_100@163.com., Cao Y; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230088, China. caoyunxia5972@ahmu.edu.cn.; NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, China. caoyunxia5972@ahmu.edu.cn.; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China, Anhui Medical University, Hefei, 230032, China. caoyunxia5972@ahmu.edu.cn., Xue R; Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230088, China. xrufeng@mail.ustc.edu.cn.; NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, China. xrufeng@mail.ustc.edu.cn.; Key Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China, Anhui Medical University, Hefei, 230032, China. xrufeng@mail.ustc.edu.cn.
Source: Cell biology and toxicology [Cell Biol Toxicol] 2026 Jan 13; Vol. 42 (1), pp. 20. Date of Electronic Publication: 2026 Jan 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 8506639 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6822 (Electronic) Linking ISSN: 07422091 NLM ISO Abbreviation: Cell Biol Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1573-6822
DOI:10.1007/s10565-026-10138-7