Disordered DNA-binding motif forms a modulation site for inhibiting the cancer immunotherapy target TREX1.
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| Title: | Disordered DNA-binding motif forms a modulation site for inhibiting the cancer immunotherapy target TREX1. |
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| Authors: | Huang KW; College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan., Yu Tsai C; College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan., Wu CY; College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan., Lin WC; Department of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei City, Taiwan., Wu MT; College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan., Hsu KC; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11011, Taiwan.; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11011, Taiwan., Yu Yang C; Institute of Biomedical Engineering, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan., Chang IY; College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan., Liu HM; Department of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei City, Taiwan., Chu JW; College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Biomedical Engineering, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan., Hsiao YY; College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Center for Intelligent Drug Systems and Smart Bio-devices (IDS2B), National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan.; Drug Development and Value Creation Research Center, Center for Cancer Research, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.; Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung 807378, Taiwan. |
| Source: | Nucleic acids research [Nucleic Acids Res] 2026 Jan 14; Vol. 54 (2). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1362-4962 |
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| DOI: | 10.1093/nar/gkaf1511 |
