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Brain-derived tau for monitoring brain injury in acute ischemic stroke.

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Title: Brain-derived tau for monitoring brain injury in acute ischemic stroke.
Authors: Vlegels N; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany., Knuth NL; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany., Steiner KA; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany., Zhang L; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany., Vix AL; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany., Moumin D; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Department of Neurology and Stroke, University Hospital Tübingen, 72076 Tübingen, Germany., Mirzen I; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Department of Neurology and Stroke, University Hospital Tübingen, 72076 Tübingen, Germany., Khalifeh N; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany., Forster C; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany., Gesierich B; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Medical Image Analysis Center (MIAC) and Department of Biomedical Engineering, University of Basel, 4051 Basel, Switzerland., Müller F; Department of Radiology, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Lohse P; Department of Radiology, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Filler J; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Graduate School for Systemic Neurosciences, Ludwig-Maximilians-University, 82152 Munich, Germany., Fang R; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany., Klein M; Department of Neurology, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Dimitriadis K; Department of Neurology, LMU University Hospital, LMU Munich, 81377 Munich, Germany., Franzmeier N; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, 413 90 Gothenburg, Sweden., Liebig T; Institute of Neuroradiology, LMU University Hospital, LMU Munich, 81377 Munich Germany., Endres M; Department of Neurology and Experimental Neurology, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; German Center for Cardiovascular Diseases (DZHK) Berlin, 10785 Berlin, Germany.; Center for Stroke Research Berlin (CSB), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; German Center for Mental Health (DZPG), 10117 Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE), 10117 Berlin, Germany., Goertler M; Department of Neurology, University Hospital, Otto-von-Guericke University Magdeburg, 39120 Magdeburg, Germany.; German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany., Petzold GC; Department of Vascular Neurology, University Hospital Bonn, 53127 Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany., Wunderlich S; Department of Neurology, Klinikum rechts der Isar School of Medicine, Technical University of Munich, 81675 Munich, Germany., Zerr I; Department of Neurology, University Medical Center Göttingen, 37075 Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany., Field TS; Division of Neurology, Stroke Program, University of British Columbia, Vancouver V6T 2B5, Canada., Pham M; Department of Neuroradiology, Würzburg University Hospital, 97080 Würzburg, Germany., Swartz RH; Division of Neurology, Sunnybrook Health Sciences Centre, Toronto M4N 3M5, Canada., Poli S; Department of Neurology and Stroke, University Hospital Tübingen, 72076 Tübingen, Germany., Berrouschot J; Klinik für Neurologie, Klinikum Altenburger Land, 04600 Altenburg, Germany., Zafar A; St. Michael's Hospital, Toronto M5B 1W8, Canada., Schneider H; Department of Neurology, University Hospital Augsburg, 86156 Augsburg, Germany.; Medical Faculty, Technische Universität Dresden, 01307 Dresden, Germany., Shankar JJ; Department of Radiology, University of Manitoba, Winnipeg R3A 1R9, Canada., Aamodt AH; Department of Neurology, Oslo University Hospital, 0424 Oslo, Norway., Minnerup J; Department of Neurology, University Hospital Münster, University of Münster, 48149 Münster, Germany.; Department of Neurology, University of Lübeck and University Hospital Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany., Mandzia JL; Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, N5A 5A5 London, Canada., Reimann G; Klinikum Dortmund, Klinikum der Universität Witten/Herdecke, 44137 Dortmund, Germany., Psychogios MN; Department of Neuroradiology, University Hospital Basel, 4031 Basel, Switzerland., Mundiyanapurath S; Department of Neurology, Heidelberg University Hospital, 69120 Heidelberg, Germany., Reich A; Department of Neurology, University Hospital RWTH Aachen, 52074 Aachen, Germany., Yeo LLL; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore., Duering M; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Medical Image Analysis Center (MIAC) and Department of Biomedical Engineering, University of Basel, 4051 Basel, Switzerland., Reidler P; Medical Image Analysis Center (MIAC) and Department of Biomedical Engineering, University of Basel, 4051 Basel, Switzerland., Goyal M; Department of Diagnostic Imaging, Cumming School of Medicine, University of Calgary, Calgary T2N 1N4, Canada., Tymianski M; NoNO Inc., Toronto M5V 1E7, Canada., Hill MD; Department of Clinical Neurosciences and Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary T2N 2T9, Canada., Dichgans M; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE) Munich, 81377 Munich, Germany.; German Center for Cardiovascular Research (DZHK) Munich, 80636 Munich, Germany., Tiedt S; Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, 81377 Munich, Germany.
Corporate Authors: DEMDAS study group, ESCAPE-NEXT biomarker substudy investigators‡, DEMDAS study group collaborators, ESCAPE-NEXT biomarker substudy investigators
Source: Science translational medicine [Sci Transl Med] 2026 Jan 14; Vol. 18 (832), pp. eadz1280. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1946-6242
DOI:10.1126/scitranslmed.adz1280