Novel therapeutic potential of the PARP inhibitor talazoparib in synovial sarcoma and its combined effect with ATR inhibitor.
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| Title: | Novel therapeutic potential of the PARP inhibitor talazoparib in synovial sarcoma and its combined effect with ATR inhibitor. |
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| Authors: | Honda N; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Molecular and Genomic Biomedicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Taniguchi H; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. hirokazu_pc@nagasaki-u.ac.jp.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan. hirokazu_pc@nagasaki-u.ac.jp.; Clinical Oncology Center, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. hirokazu_pc@nagasaki-u.ac.jp., Ono S; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan., Hayashi F; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan., Imamura E; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan., Gyotoku H; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan., Takemoto S; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan., Takazono T; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan., Ishimoto H; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan., Sakamoto N; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan., Obase Y; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan., Masutani M; Department of Molecular and Genomic Biomedicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Nishino T; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan.; Department of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Mukae H; Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan. |
| Source: | Discover oncology [Discov Oncol] 2026 Jan 15; Vol. 17 (1), pp. 279. Date of Electronic Publication: 2026 Jan 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: United States NLM ID: 101775142 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-6011 (Electronic) Linking ISSN: 27306011 NLM ISO Abbreviation: Discov Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2730-6011 |
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| DOI: | 10.1007/s12672-026-04422-5 |
