USP8-mediated mitochondrial regulation in osteoclasts is essential for skeletal development.

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Title: USP8-mediated mitochondrial regulation in osteoclasts is essential for skeletal development.
Authors: Chaugule S; Department of Genetic and Cellular Medicine, UMass Chan Medical School, Worcester, MA, USA.; Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.; Horae Gene Therapy Center, UMass Chan Medical School, Worcester, MA, USA., Yang YS; Department of Genetic and Cellular Medicine, UMass Chan Medical School, Worcester, MA, USA.; Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.; Horae Gene Therapy Center, UMass Chan Medical School, Worcester, MA, USA., Sato T; Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.; Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Li Weibo Institute for Rare Diseases Research, UMass Chan Medical School, Worcester, MA, USA., Mayer E; Department of Genetic and Cellular Medicine, UMass Chan Medical School, Worcester, MA, USA.; Department of Medicine, UMass Chan Medical School, Worcester, MA, USA.; Horae Gene Therapy Center, UMass Chan Medical School, Worcester, MA, USA., Shim JH; Department of Genetic and Cellular Medicine, UMass Chan Medical School, Worcester, MA, USA. jaehyuck.shim@umassmed.edu.; Department of Medicine, UMass Chan Medical School, Worcester, MA, USA. jaehyuck.shim@umassmed.edu.; Horae Gene Therapy Center, UMass Chan Medical School, Worcester, MA, USA. jaehyuck.shim@umassmed.edu.; Li Weibo Institute for Rare Diseases Research, UMass Chan Medical School, Worcester, MA, USA. jaehyuck.shim@umassmed.edu.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Jan 15; Vol. 83 (1), pp. 72. Date of Electronic Publication: 2026 Jan 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-9071
DOI:10.1007/s00018-025-06012-0