Host-derived interleukin-1α drives tumor immunosuppression by reprogramming tumor-associated myeloid cells.
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| Title: | Host-derived interleukin-1α drives tumor immunosuppression by reprogramming tumor-associated myeloid cells. |
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| Authors: | Keerthi Raja MR; Department of Biological Sciences, University of South Carolina, Columbia, SC, USA.; Oncology Division, Washington University School of Medicine, St Louis, USA., Gupta G; Department of Biological Sciences, University of South Carolina, Columbia, SC, USA., Atkinson G; Department of Biological Sciences, University of South Carolina, Columbia, SC, USA., Kathrein K; Department of Biological Sciences, University of South Carolina, Columbia, SC, USA., Armstrong A; Department of Biological Sciences, University of South Carolina, Columbia, SC, USA., Gower RM; Department of Chemical Engineering and Biomedical Engineering, University of South Carolina, Columbia, SC, USA., Roninson IB; Department of Drug Discovery & Biomedical Sciences (DDBS), College of Pharmacy, University of South Carolina, Columbia, SC, USA., Broude EV; Department of Drug Discovery & Biomedical Sciences (DDBS), College of Pharmacy, University of South Carolina, Columbia, SC, USA., Chen M; Department of Drug Discovery & Biomedical Sciences (DDBS), College of Pharmacy, University of South Carolina, Columbia, SC, USA., Ji H; Department of Drug Discovery & Biomedical Sciences (DDBS), College of Pharmacy, University of South Carolina, Columbia, SC, USA., Lim CU; Department of Drug Discovery & Biomedical Sciences (DDBS), College of Pharmacy, University of South Carolina, Columbia, SC, USA., Wang H; Department of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ, USA., Fan D; Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC, USA., Xu P; Department of Drug Discovery & Biomedical Sciences (DDBS), College of Pharmacy, University of South Carolina, Columbia, SC, USA., Li J; Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, USA.; Division of Chemical Biology, and Medicinal Chemistry, College of Pharmacy, University of Texas at Austin, Austin, TX, USA., Zhou G; Georgia Cancer Center, Department of Medicine, Medical College of Georgia, Augusta, GA, USA., Chen H; Department of Biological Sciences, University of South Carolina, Columbia, SC, USA. hchen@biol.sc.edu. |
| Source: | NPJ breast cancer [NPJ Breast Cancer] 2026 Jan 17; Vol. 12 (1), pp. 26. Date of Electronic Publication: 2026 Jan 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Breast Cancer Research Foundation Country of Publication: United States NLM ID: 101674891 Publication Model: Electronic Cited Medium: Print ISSN: 2374-4677 (Print) Linking ISSN: 23744677 NLM ISO Abbreviation: NPJ Breast Cancer Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2374-4677 |
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| DOI: | 10.1038/s41523-026-00890-8 |