A Phase 1 Dose-Escalation, Food Effect, and Drug-Drug Interaction Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the MALT1 Inhibitor, SGR-1505, in Healthy Volunteers.

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Title: A Phase 1 Dose-Escalation, Food Effect, and Drug-Drug Interaction Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the MALT1 Inhibitor, SGR-1505, in Healthy Volunteers.
Authors: Gupta VK; Schrödinger Inc., New York, USA., Yoo B; Schrödinger Inc., New York, USA., Weiss D; Schrödinger Inc., New York, USA., Basile FG; Schrödinger Inc., New York, USA., Schuck E; Schrödinger Inc., New York, USA., Rubino CM; Institute for Clinical Pharmacodynamics, Schenectady, NY, USA., Zhang S; Schrödinger Inc., New York, USA., Maxwell SE; Schrödinger Inc., New York, USA., Zheng W; Schrödinger Inc., New York, USA., Tan JBL; Parvus Therapeutics, South San Francisco, CA, USA., Stenehjem D; University of Minnesota, College of Pharmacy, Duluth, MN, USA., Watkins PB; Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA., Dugan M; Schrödinger Inc., New York, USA., Yin W; Schrödinger Inc., New York, USA., Wright DH; Schrödinger Inc., New York, USA., Akinsanya K; Schrödinger Inc., New York, USA., Lickliter J; Nucleus Network Ltd., Melbourne, VIC, Australia.
Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2026 Jan; Vol. 15 (1), pp. e70008.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2160-7648
DOI:10.1002/cpdd.70008