Antibodies directed against extracellular loops of FadL orthologs disrupt outer membrane integrity and neutralize infectivity of Treponema pallidum, the syphilis spirochete.
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| Title: | Antibodies directed against extracellular loops of FadL orthologs disrupt outer membrane integrity and neutralize infectivity of Treponema pallidum, the syphilis spirochete. |
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| Authors: | Delgado KN; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Department of Medicine, UConn Health, Farmington, CT, United States., Vicente CF; Department of Pediatrics, UConn Health, Farmington, CT, United States., La Vake CJ; Department of Pediatrics, UConn Health, Farmington, CT, United States., Bettin E; Department of Medicine, UConn Health, Farmington, CT, United States., Caimano MJ; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Department of Medicine, UConn Health, Farmington, CT, United States.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT, United States.; Department of Research, Connecticut Children's Research Institute, Hartford, CT, United States., Radolf JD; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Department of Medicine, UConn Health, Farmington, CT, United States.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT, United States.; Department of Research, Connecticut Children's Research Institute, Hartford, CT, United States.; Department of Immunology, UConn Health, Farmington, CT, United States.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, United States., Hawley KL; Department of Pediatrics, UConn Health, Farmington, CT, United States.; Department of Medicine, UConn Health, Farmington, CT, United States.; Department of Research, Connecticut Children's Research Institute, Hartford, CT, United States.; Department of Immunology, UConn Health, Farmington, CT, United States.; Division of Infectious Diseases and Immunology, Connecticut Children's, Hartford, CT, United States. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Jan 02; Vol. 16, pp. 1724458. Date of Electronic Publication: 2026 Jan 02 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1724458 |
