The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis.
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| Title: | The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis. |
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| Authors: | Meng F; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Du Y; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Liang J; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China., Li H; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Wang J; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Tang K; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Kong R; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Sun H; College of Pharmacy, Nankai University, Tianjin, China., Yin T; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Qin J; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Yang X; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Shan C; College of Pharmacy, Nankai University, Tianjin, China., Liu M; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Yang G; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China., Zhang J; Institute of Brain Science and Brain-inspired Research, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China., Wang Y; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China. yijiewang@sdnu.edu.cn., Zhou J; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China. junzhou@sdnu.edu.cn.; College of Life Sciences, Nankai University, Tianjin, China. junzhou@sdnu.edu.cn., Chen Y; Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Center for Cell Structure and Function, Modern Industry Institute of Biomedicine, College of Life Sciences, Shandong Normal University, Jinan, Shandong, China. yanchen@sdnu.edu.cn. |
| Source: | Nature communications [Nat Commun] 2026 Jan 20; Vol. 17 (1), pp. 614. Date of Electronic Publication: 2026 Jan 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-026-68492-3 |
