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The two-step purification method ViREn identifies a single NSUN6-mediated 5-methylcytosine modification promoting dengue virus RNA genome turnover.

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Title: The two-step purification method ViREn identifies a single NSUN6-mediated 5-methylcytosine modification promoting dengue virus RNA genome turnover.
Authors: Wu CC; Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Disease Research, Heidelberg University, Medical Faculty Heidelberg, 69120 Heidelberg, Germany., Naarmann-de Vries IS; Klaus Tschira Institute for Integrative Computational Cardiology, Heidelberg University, Medical Faculty Heidelberg, 69120 Heidelberg, Germany.; German Centre for Cardiovascular Research (DZHK)-Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany., Hartmann J; Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Disease Research, Heidelberg University, Medical Faculty Heidelberg, 69120 Heidelberg, Germany., Nidoieva Z; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Kopietz K; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Marchand V; Université de Lorraine, SMP IBSLor, EpiRNA-Seq Core Facility, 54000 Nancy, France.; Université de Lorraine, CNRS, UMR7365 IMoPA, 54000 Nancy, France., Özrendeci Z; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Lindner D; Division of Biochemistry, Mannheim Institute for Innate Immunoscience (MI3) and Mannheim Cancer Center (MCC), Heidelberg University, Medical Faculty Mannheim, 68167 Mannheim, Germany.; Center for Molecular Biology of Heidelberg University (ZMBH), German Cancer Research Center (DKFZ)-ZMBH Alliance, 69120 Heidelberg, Germany., Schelchshorn S; Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Disease Research, Heidelberg University, Medical Faculty Heidelberg, 69120 Heidelberg, Germany., Flad S; Division of Mechanisms Regulating Gene Expression, German Cancer Research Center-Deutsches Krebsforschungszentrum (DKFZ), 69120 Heidelberg, Germany., Frye M; Division of Mechanisms Regulating Gene Expression, German Cancer Research Center-Deutsches Krebsforschungszentrum (DKFZ), 69120 Heidelberg, Germany., Papavasiliou FN; Division of Immune Diversity, German Cancer Research Center-Deutsches Krebsforschungszentrum (DKFZ), 69120 Heidelberg, Germany., Schirmeister T; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Stoecklin G; Division of Biochemistry, Mannheim Institute for Innate Immunoscience (MI3) and Mannheim Cancer Center (MCC), Heidelberg University, Medical Faculty Mannheim, 68167 Mannheim, Germany.; Center for Molecular Biology of Heidelberg University (ZMBH), German Cancer Research Center (DKFZ)-ZMBH Alliance, 69120 Heidelberg, Germany., Schott J; Division of Biochemistry, Mannheim Institute for Innate Immunoscience (MI3) and Mannheim Cancer Center (MCC), Heidelberg University, Medical Faculty Mannheim, 68167 Mannheim, Germany.; Center for Molecular Biology of Heidelberg University (ZMBH), German Cancer Research Center (DKFZ)-ZMBH Alliance, 69120 Heidelberg, Germany., Motorin Y; Université de Lorraine, SMP IBSLor, EpiRNA-Seq Core Facility, 54000 Nancy, France.; Université de Lorraine, CNRS, UMR7365 IMoPA, 54000 Nancy, France., Tuorto F; Division of Biochemistry, Mannheim Institute for Innate Immunoscience (MI3) and Mannheim Cancer Center (MCC), Heidelberg University, Medical Faculty Mannheim, 68167 Mannheim, Germany.; Center for Molecular Biology of Heidelberg University (ZMBH), German Cancer Research Center (DKFZ)-ZMBH Alliance, 69120 Heidelberg, Germany., Dieterich C; Klaus Tschira Institute for Integrative Computational Cardiology, Heidelberg University, Medical Faculty Heidelberg, 69120 Heidelberg, Germany.; German Centre for Cardiovascular Research (DZHK)-Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany., Helm M; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Ruggieri A; Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Disease Research, Heidelberg University, Medical Faculty Heidelberg, 69120 Heidelberg, Germany.
Source: Nucleic acids research [Nucleic Acids Res] 2026 Jan 14; Vol. 54 (2).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1362-4962
DOI:10.1093/nar/gkag003