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Quantitative assessment of neonatal health using dried blood spot metabolite profiles and deep learning.

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Title: Quantitative assessment of neonatal health using dried blood spot metabolite profiles and deep learning.
Authors: Chang AL; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Reiss JD; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Culos A; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Becker M; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Mayo JA; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Marić I; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., De Francesco D; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Phongpreecha T; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA., Espinosa CA; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Mataraso SJ; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Berson E; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA., Kim Y; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Xue L; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Xie F; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Shu CH; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Fallahzadeh R; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Bidoki NH; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Xenochristou M; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Zhang M; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Profit J; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Lee HC; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093, USA., Gaudillière B; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Angst MS; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Hawken S; Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, Canada., Wilson K; Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, Canada.; Bruyère Health Research Institute, Ottawa, ON K1R 6M1, Canada., Stevenson DK; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Shaw GM; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA., Sylvester KG; Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA., Aghaeepour N; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Biomedical Data Science, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.
Source: Science translational medicine [Sci Transl Med] 2026 Jan 21; Vol. 18 (833), pp. eadv4942. Date of Electronic Publication: 2026 Jan 21.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.adv4942