Betanin-encapsulated nanoparticles mitigate neurotoxicity against AlCl3-induced Alzheimer's disease via modulation of AChE/TNF-α/IL-1β expression.

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Title: Betanin-encapsulated nanoparticles mitigate neurotoxicity against AlCl3-induced Alzheimer's disease via modulation of AChE/TNF-α/IL-1β expression.
Authors: Razzaq R; Department of Biosciences, COMSATS University Islamabad (CUI), Park Road, Islamabad, 45550, Pakistan., Ahmed T; Neurobiology Laboratory, Department of Healthcare Biotechnology, Atta-Ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, 44000, Pakistan., Butt AM; Department of Biosciences, COMSATS University Islamabad (CUI), Park Road, Islamabad, 45550, Pakistan; Comprehensive Cancer Centre, Guy's Hospital, King's College London, SE1 9RT, London, United Kingdom., Jabeen Z; Department of Biosciences, COMSATS University Islamabad (CUI), Park Road, Islamabad, 45550, Pakistan., Khalid A; Azra Naheed Medical College, 17km Raiwind Rd, Kot Araian, Lahore, Pakistan., Shahid I; Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, AlAbidiyah, P.O. Box 13578, Makkah, 21955, Saudi Arabia., Alzahrani AR; Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, AlAbidiyah, P.O. Box 13578, Makkah, 21955, Saudi Arabia., Rehman S; Department of Biosciences, COMSATS University Islamabad (CUI), Park Road, Islamabad, 45550, Pakistan. Electronic address: sidrarehman@comsats.edu.pk.
Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2026 Feb 19; Vol. 801, pp. 153293. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1090-2104
DOI:10.1016/j.bbrc.2026.153293