Combining percutaneous endoscopic lumbar discectomy with ozone injection for lumbar disc herniation and ferroptosis suppression: a randomized clinical trial.

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Title: Combining percutaneous endoscopic lumbar discectomy with ozone injection for lumbar disc herniation and ferroptosis suppression: a randomized clinical trial.
Authors: Wang H; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Xu L; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Deng J; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.; 4Department of Pain, Wuxi Xishan People's Hospital, Wuxi, China., Qiu X; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Dong C; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Hu Y; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Li Q; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Mei T; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Chen S; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Wu Y; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Miao L; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Huang F; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Huang M; 3Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Key Laboratory of Mental Disorder's Management of Zhejiang Province, Zhejiang Engineering Center for Mathematical Mental Health, Hangzhou, Zhejiang; and., Cheng Y; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Sun J; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Yu L; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.
Source: Journal of neurosurgery. Spine [J Neurosurg Spine] 2026 Jan 23; Vol. 44 (4), pp. 537-546. Date of Electronic Publication: 2026 Jan 23.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Association of Neurological Surgeons Country of Publication: United States NLM ID: 101223545 Publication Model: Electronic Cited Medium: Internet ISSN: 1547-5646 (Electronic) Linking ISSN: 15475646 NLM ISO Abbreviation: J Neurosurg Spine Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1547-5646
DOI:10.3171/2025.9.SPINE25581