Combining percutaneous endoscopic lumbar discectomy with ozone injection for lumbar disc herniation and ferroptosis suppression: a randomized clinical trial.

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Title: Combining percutaneous endoscopic lumbar discectomy with ozone injection for lumbar disc herniation and ferroptosis suppression: a randomized clinical trial.
Authors: Wang H; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Xu L; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Deng J; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.; 4Department of Pain, Wuxi Xishan People's Hospital, Wuxi, China., Qiu X; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Dong C; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Hu Y; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Li Q; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Mei T; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Chen S; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Wu Y; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Miao L; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Huang F; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Huang M; 3Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Key Laboratory of Mental Disorder's Management of Zhejiang Province, Zhejiang Engineering Center for Mathematical Mental Health, Hangzhou, Zhejiang; and., Cheng Y; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Sun J; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou., Yu L; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.
Source: Journal of neurosurgery. Spine [J Neurosurg Spine] 2026 Jan 23; Vol. 44 (4), pp. 537-546. Date of Electronic Publication: 2026 Jan 23.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Association of Neurological Surgeons Country of Publication: United States NLM ID: 101223545 Publication Model: Electronic Cited Medium: Internet ISSN: 1547-5646 (Electronic) Linking ISSN: 15475646 NLM ISO Abbreviation: J Neurosurg Spine Subsets: MEDLINE
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  Data: Combining percutaneous endoscopic lumbar discectomy with ozone injection for lumbar disc herniation and ferroptosis suppression: a randomized clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Xu+L%22">Xu L</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Deng+J%22">Deng J</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.; 4Department of Pain, Wuxi Xishan People's Hospital, Wuxi, China.<br /><searchLink fieldCode="AU" term="%22Qiu+X%22">Qiu X</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Dong+C%22">Dong C</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Mei+T%22">Mei T</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Miao+L%22">Miao L</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Huang+F%22">Huang F</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; 3Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Key Laboratory of Mental Disorder's Management of Zhejiang Province, Zhejiang Engineering Center for Mathematical Mental Health, Hangzhou, Zhejiang; and.<br /><searchLink fieldCode="AU" term="%22Cheng+Y%22">Cheng Y</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.<br /><searchLink fieldCode="AU" term="%22Yu+L%22">Yu L</searchLink>; 1The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou First People's Hospital, Hangzhou.; 2Department of Pain, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou.
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  Data: <searchLink fieldCode="JN" term="%22101223545%22">Journal of neurosurgery. Spine</searchLink> [J Neurosurg Spine] 2026 Jan 23; Vol. 44 (4), pp. 537-546. <i>Date of Electronic Publication: </i>2026 Jan 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+of+Neurological+Surgeons%22">American Association of Neurological Surgeons </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101223545 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1547-5646 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215475646%22">15475646 </searchLink><i>NLM ISO Abbreviation: </i>J Neurosurg Spine <i>Subsets: </i>MEDLINE
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        Value: 10.3171/2025.9.SPINE25581
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        Text: English
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      – TitleFull: Combining percutaneous endoscopic lumbar discectomy with ozone injection for lumbar disc herniation and ferroptosis suppression: a randomized clinical trial.
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