Scalable and multiplexed recorders of gene regulation dynamics across weeks.

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Title: Scalable and multiplexed recorders of gene regulation dynamics across weeks.
Authors: Zheng L; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA., Shi D; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA., Yan Y; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA., Zhou B; Department of Computer Science and Technology, University of Cambridge, Cambridge, UK., Lim J; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA., Hou Y; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA., An B; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Adhinarta JK; Department of Computer Science, Boston College, Boston, MA, USA., Lin M; Department of Computer Science, Boston College, Boston, MA, USA., Ko B; Nash Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Joesten WC; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA., Gautam M; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA., Huez EDM; Kresge Hearing Research Institute and Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA., Kim EC; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Klyder EG; Department of Chemistry, University of Michigan, Ann Arbor, MI, USA., Chang B; Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA., Pitchiaya S; Department of Urology, University of Michigan, Ann Arbor, MI, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Roberts MT; Kresge Hearing Research Institute and Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA., Cai DJ; Nash Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Boyden ES; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Yang Tan Collective and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA., Wei D; Department of Computer Science, Boston College, Boston, MA, USA., Liò P; Department of Computer Science and Technology, University of Cambridge, Cambridge, UK., Linghu C; Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA. linghu@umich.edu.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA. linghu@umich.edu.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. linghu@umich.edu.
Source: Nature [Nature] 2026 Apr; Vol. 652 (8111), pp. 1038-1048. Date of Electronic Publication: 2026 Jan 26.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-026-10156-9