Modulation of the miR-485-3p/PGC-1α Pathway by ASO-Loaded Nanoparticles Attenuates ALS Pathogenesis.

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Title: Modulation of the miR-485-3p/PGC-1α Pathway by ASO-Loaded Nanoparticles Attenuates ALS Pathogenesis.
Authors: Ryu IS; BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea., Ha DI; BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea., Jung YJ; BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea., Lee HJ; BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea., Kim I; BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea., Lim YN; BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea., Min HS; BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea., Kim SH; Department of Neurology, College of Medicine, Hanyang University, 222, Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of Korea., Yoon I; BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea., Cho HJ; Department of Biomedical Laboratory Science, College of Medical Science, Konyang University, 158 Gwanjeodong-ro, Seo-gu, Daejeon 35365, Republic of Korea., Ryu JH; BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Jan 07; Vol. 27 (2). Date of Electronic Publication: 2026 Jan 07.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1422-0067
DOI:10.3390/ijms27020615