Integrated multi-omics and single-cell analysis identify SERPINE1 as a key mediator of the inflammatory tumor microenvironment in PDAC.
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| Title: | Integrated multi-omics and single-cell analysis identify SERPINE1 as a key mediator of the inflammatory tumor microenvironment in PDAC. |
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| Authors: | Wang D; Department of Liver Transplantation, First Central Hospital of Tianjin Medical University, Tianjin, China.; Tianjin Key Laboratory of Molecular and Treatment of Liver Cancer, Tianjin First Central Hospital, Tianjin, China., Chen Q; Department of General Surgery, Peking University Third Hospital, Beijing, China., Li CM; Department of Liver Transplantation, First Central Hospital of Tianjin Medical University, Tianjin, China.; Department of General Surgery, Tianjin Fifth Central Hospital, Tianjin, China., Xie Y; Department of Liver Transplantation, First Central Hospital of Tianjin Medical University, Tianjin, China.; Tianjin Key Laboratory of Molecular and Treatment of Liver Cancer, Tianjin First Central Hospital, Tianjin, China., Yuan C; Department of General Surgery, Peking University Third Hospital, Beijing, China., Lang R; Department of Hepatobiliary and Pancreaticosplenic Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China., Jiang WT; Department of Liver Transplantation, First Central Hospital of Tianjin Medical University, Tianjin, China.; Tianjin Key Laboratory of Molecular and Treatment of Liver Cancer, Tianjin First Central Hospital, Tianjin, China. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Jan 12; Vol. 16, pp. 1716878. Date of Electronic Publication: 2026 Jan 12 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1716878 |
