Nickel-Catalyzed Enantioselective Reductive Alkenylation of N-Pyridyl Aldimines via a Mechanism of Elementary 1,4-Addition.

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Title: Nickel-Catalyzed Enantioselective Reductive Alkenylation of N-Pyridyl Aldimines via a Mechanism of Elementary 1,4-Addition.
Authors: Zhao M; State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 2199 Lishui Road, Nanshan District, Shenzhen 518055, China., Xiao B; Lab of Computational Chemistry and Drug Design, State Key Laboratory of Chemical Oncogenomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China.; Hoffmann Institute of Advanced Materials, School of Food and Drug, Shenzhen Polytechnic University, Shenzhen 518055, China., Sun L; State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 2199 Lishui Road, Nanshan District, Shenzhen 518055, China., Zhou JS; State Key Laboratory of Chemical Oncogenomics, Shenzhen Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 2199 Lishui Road, Nanshan District, Shenzhen 518055, China.
Source: Organic letters [Org Lett] 2026 Feb 06; Vol. 28 (5), pp. 1720-1726. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1523-7052
DOI:10.1021/acs.orglett.5c05222