Loss of MicroRNA-29b promotes DNMT3b-mediated STING downregulation to attenuate radiotherapy-induced antitumor immunity in KRAS-mutated colorectal cancer.
Saved in:
| Title: | Loss of MicroRNA-29b promotes DNMT3b-mediated STING downregulation to attenuate radiotherapy-induced antitumor immunity in KRAS-mutated colorectal cancer. |
|---|---|
| Authors: | Chang HY; Institute of Molecular Medicine and Bioengineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.; Translation Research Core, China Medical University Hospital, China Medical University, Taichung, Taiwan., Chen JY; Translation Research Core, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Center of Proton therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan., Ke TW; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung, Taiwan.; School of Chinese Medicine and Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan., Jiang YW; Translation Research Core, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Center of Proton therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan., Hong WZ; Translation Research Core, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Center of Proton therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan., Tsai YY; Department of Colorectal Surgery, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan., Chiang SF; Lab of Precision Medicine, Feng-Yuan Hospital, Ministry of Health and Welfare, Taichung, Taiwan., Lin YS; Department of Chest Surgery, China Medical University Hospital, China Medical University, Taichung, Taiwan., Huang CH; Center of Proton therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan., Chen TH; Department of Surgery, China Medical University Hospital, China Medical University, Taichung, Taiwan., Chao KSC; Center of Proton therapy, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Department of Radiation Oncology, China Medical University Hospital, China Medical University, Taichung, Taiwan., Huang KC; Translation Research Core, China Medical University Hospital, China Medical University, Taichung, Taiwan. chihyang0425@mail.cmu.edu.tw.; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan. chihyang0425@mail.cmu.edu.tw.; Cancer Biology and Precision Therapeutics Center, China Medical University, Taichung, Taiwan. chihyang0425@mail.cmu.edu.tw.; Office of Research and Development, Asia University, Taichung, Taiwan. chihyang0425@mail.cmu.edu.tw. |
| Source: | NPJ precision oncology [NPJ Precis Oncol] 2026 Jan 28; Vol. 10 (1). Date of Electronic Publication: 2026 Jan 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 2397-768X |
|---|---|
| DOI: | 10.1038/s41698-026-01290-8 |
