Covalent modification of a glutamic acid inspired by HaloTag technology.

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Title: Covalent modification of a glutamic acid inspired by HaloTag technology.
Authors: Zhang R; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Liu J; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Gasper R; Crystallography and Biophysics Facility, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Unger A; Lead Discovery Center GmbH, Dortmund, Germany., Kaschani F; Analytics Core Facility Essen (ACE), Chemical Biology, Faculty of Biology, University of Duisburg-Essen, Essen, Germany., Kaiser M; Analytics Core Facility Essen (ACE), Chemical Biology, Faculty of Biology, University of Duisburg-Essen, Essen, Germany., Janning P; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Waldmann H; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany. Herbert.waldmann@mpi-dortmund.mpg.de.; Faculty of Chemistry and Chemical Biology, Technical University Dortmund, Dortmund, Germany. Herbert.waldmann@mpi-dortmund.mpg.de.
Source: Nature communications [Nat Commun] 2026 Jan 30; Vol. 17 (1), pp. 1257. Date of Electronic Publication: 2026 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-68999-9